Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/95460
DC Field | Value | Language |
---|---|---|
dc.contributor | Department of Applied Biology and Chemical Technology | en_US |
dc.creator | Chu, JCH | en_US |
dc.creator | Shao, C | en_US |
dc.creator | Ha, SYY | en_US |
dc.creator | Fong, WP | en_US |
dc.creator | Wong, CTT | en_US |
dc.creator | Ng, DKP | en_US |
dc.date.accessioned | 2022-09-19T02:22:07Z | - |
dc.date.available | 2022-09-19T02:22:07Z | - |
dc.identifier.issn | 2047-4830 | en_US |
dc.identifier.uri | http://hdl.handle.net/10397/95460 | - |
dc.language.iso | en | en_US |
dc.publisher | Royal Society of Chemistry | en_US |
dc.rights | This journal is © The Royal Society of Chemistry 2021 | en_US |
dc.rights | The following publication Chu, J. C., Shao, C., Ha, S. Y., Fong, W. P., Wong, C. T., & Ng, D. K. (2021). One-pot peptide cyclisation and surface modification of photosensitiser-loaded red blood cells for targeted photodynamic therapy. Biomaterials Science, 9(23), 7832-7837 is available at https://doi.org/10.1039/d1bm01306h. | en_US |
dc.title | One-pot peptide cyclisation and surface modification of photosensitiser-loaded red blood cells for targeted photodynamic therapy | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.spage | 7832 | en_US |
dc.identifier.epage | 7837 | en_US |
dc.identifier.volume | 9 | en_US |
dc.identifier.issue | 23 | en_US |
dc.identifier.doi | 10.1039/d1bm01306h | en_US |
dcterms.abstract | We report herein a one-pot approach to cyclise a tumour-Targeting peptide and conjugate it on the surface of red blood cells loaded with a boron dipyrromethene-based photosensitiser using a bifunctional linker consisting of a bis(bromomethyl)phenyl unit and an ortho-phthalaldehyde unit. This cell-based photosensitiser with surface modification with cyclic RGD peptide moieties can selectively bind against the αvβ3 integrin-overexpressed cancer cells, leading to enhanced photocytotoxicity. The results demonstrate that this facile strategy is effective for live-cell surface modification for a wide range of applications. | en_US |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Biomaterials science, 7 Dec. 2021, v. 9, no. 23, p. 7832-7837 | en_US |
dcterms.isPartOf | Biomaterials science | en_US |
dcterms.issued | 2021-12-07 | - |
dc.identifier.scopus | 2-s2.0-85120174694 | - |
dc.identifier.pmid | 34726672 | - |
dc.identifier.eissn | 2047-4849 | en_US |
dc.description.validate | 202209 bcww | en_US |
dc.description.oa | Accepted Manuscript | en_US |
dc.identifier.FolderNumber | ABCT-0009 | - |
dc.description.fundingSource | RGC | en_US |
dc.description.pubStatus | Published | en_US |
dc.identifier.OPUS | 59357385 | - |
Appears in Collections: | Journal/Magazine Article |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Shao_One-Pot_Peptide_Cyclisation.pdf | Pre-Published version | 985.88 kB | Adobe PDF | View/Open |
Page views
73
Last Week
0
0
Last month
Citations as of Sep 22, 2024
Downloads
76
Citations as of Sep 22, 2024
SCOPUSTM
Citations
9
Citations as of Sep 26, 2024
WEB OF SCIENCETM
Citations
9
Citations as of Sep 26, 2024
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.