Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/91677
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dc.contributorDepartment of Applied Biology and Chemical Technology-
dc.creatorZhang, K-
dc.creatorTong, WW-
dc.creatorWang, XH-
dc.creatorLau, JYN-
dc.date.accessioned2021-11-24T06:07:39Z-
dc.date.available2021-11-24T06:07:39Z-
dc.identifier.issn2096-5303-
dc.identifier.urihttp://hdl.handle.net/10397/91677-
dc.language.isoenen_US
dc.publisherOxford University Pressen_US
dc.rights© The Author(s) 2020. Published by Oxford University Press on behalf of the West China School of Medicine & West China Hospital of Sichuan University.en_US
dc.rightsThis is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
dc.rightsThe following publication Zhang, K., Tong, W., Wang, X., & Lau, J. Y. N. (2020). Estimated prevalence and viral transmissibility in subjects with asymptomatic SARS-CoV-2 infections in Wuhan, China. Precision Clinical Medicine, 3(4), 301-305 is available at https://doi.org/10.1093/pcmedi/pbaa032en_US
dc.subjectAsymptomatic carriersen_US
dc.subjectInfectionen_US
dc.subjectCOVID-19en_US
dc.titleEstimated prevalence and viral transmissibility in subjects with asymptomatic SARS-CoV-2 infections in Wuhan, Chinaen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage301-
dc.identifier.epage305-
dc.identifier.volume3-
dc.identifier.issue4-
dc.identifier.doi10.1093/pcmedi/pbaa032-
dcterms.abstractThe role of subjects with asymptomatic SARS-CoV-2 infection in the current pandemic is not well-defined. Based on two different approaches to estimate the culminative attack rate (seroprevalence of antibodies against SARS-CoV-2, and a four compartment mathematical model) and the reported number of patients with COVID-19, the ratio of asymptomatic versus symptomatic SARS-CoV-2 infection was estimated to be 7 (95% CI: 2.8-12.4) in Wuhan, Hubei, China, the first epicenter of this pandemic, which has settled with no new cases. Together with detailed recording of the contact sources in a cohort of patients, and applying the estimations to an established mathematical model, the viral transmissibility of the subjects with asymptomatic SARS-CoV-2 infection is around 10% of that of the symptomatic patients (95% CI: 7.6%-12.3%). Public health measures/policies should address this important pool of infectious source in combat against this viral pandemic.-
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationPrecision clinical medicine, Dec. 2020, v. 3, no. 4, p. 301-305-
dcterms.isPartOfPrecision clinical medicine-
dcterms.issued2020-12-
dc.identifier.isiWOS:000661917500008-
dc.identifier.eissn2516-1571-
dc.description.validate202111 bchy-
dc.description.oaVersion of Recorden_US
dc.identifier.FolderNumberOA_Scopus/WOSen_US
dc.description.pubStatusPublisheden_US
dc.description.oaCategoryCCen_US
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