Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/106249
Title: | Prevalence and molecular characterization of cefotaxime-resistant <i>Salmonella</i> strains recovered from retail meat samples in Shenzhen, China, during 2014-2017 | Authors: | Yang, C Chen, KC Ye, LW Heng, H Yang, XM Chan, EWC Chen, S |
Issue Date: | Sep-2023 | Source: | Microbiology spectrum, Sept.-Oct. 2023, v. 11, no. 5, e04886-22 | Abstract: | In this work, we collected foodborne Salmonella strains in Shenzhen, China, during 2014-2017 and investigated the genetic profile of all cefotaxime-resistant isolates in the collection. The strains were subjected to antimicrobial susceptibility tests, whole-genome sequencing, bioinformatics analysis, and conjugation studies. A total of 79 cefotaxime-resistant Salmonella were identified and found to exhibit multidrug resistance. Resistance rate recorded during the study period increased from 1.9% to 9.1%. Salmonella Typhimurium was the predominant serovar, and CTX-M family genes were dominant among the ESBLs genes detected. Notably, CTX-M-bearing plasmids or transposons often contain other drug resistance genes. Furthermore, a combination of CTX-M-55 and CTX-M-65 genes was detected for the first time in foodborne Salmonella strains. Our findings reveal the prevalence and molecular characteristics of cefotaxime-resistant foodborne Salmonella strains in southern China. | Keywords: | Salmonella CTX-M Cefotaxime Multidrug resistance Plasmid Food |
Publisher: | American Society for Microbiology | Journal: | Microbiology spectrum | EISSN: | 2165-0497 | DOI: | 10.1128/spectrum.04886-22 | Rights: | Copyright © 2023 Yang et al. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 International License (https://creativecommons.org/licenses/by/4.0/). The following publication Yang C, Chen K, Ye L, Heng H, Yang X, Wai-chi Chan E, Chen S. 2023. Prevalence and molecular characterization of cefotaxime-resistant Salmonella strains recovered from retail meat samples in Shenzhen, China, during 2014–2017. Microbiol Spectr 11:e04886-22 is available at https://dx.doi.org/10.1128/spectrum.04886-22. |
Appears in Collections: | Journal/Magazine Article |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Yang_Prevalence_Molecular_Characterization.pdf | 2.52 MB | Adobe PDF | View/Open |
Page views
9
Citations as of Jun 30, 2024
Downloads
1
Citations as of Jun 30, 2024
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.