Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/81255
Title: Role of corneal biomechanical properties in predicting of speed of myopic progression in children wearing orthokeratology lenses or single-vision spectacles
Authors: Wan, K 
Cheung, SW 
Wolffsohn, JS
Orr, JB
Cho, P 
Keywords: Cornea
Myopia
Orthokeratology
Issue Date: 2018
Publisher: BMJ Group
Source: BMJ Open ophthalmology, 2018, v. 3, no. 1, e000204 How to cite?
Journal: BMJ Open ophthalmology 
Abstract: Objective To determine the characteristics of children who were likely to progress rapidly and gain the greatest benefit from orthokeratology (ortho-k) treatment. Methods and analysis The files of 113 children who participated in two myopia control studies and wore either ortho-k lenses (n=62) or single-vision spectacles (SVS) (n=51) were reviewed. Baseline cycloplegic subjective refraction, central corneal thickness, axial length, keratometry, intraocular pressure, corneal biomechanical properties and 24-month axial length data were retrieved and analysed. Results Multivariate analysis showed that there was significant negative correlation between axial elongation and baseline age and corneal hysteresis (p<0.05) in the SVS group. In the ortho-k group, only baseline age was significantly and negatively associated with axial elongation (p<0.01). Conclusion Corneal biomechanical properties and baseline age can predict the rate of axial elongation in myopic children. It may be beneficial for younger myopic children with low corneal hysteresis to commence ortho-k treatment as early as possible.
URI: http://hdl.handle.net/10397/81255
EISSN: 2397-3269
DOI: 10.1136/bmjophth-2018-000204
Rights: © Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.
This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0.
The following publication Wan K, Cheung SW, Wolffsohn JS, et al Role of corneal biomechanical properties in predicting of speed of myopic progression in children wearing orthokeratology lenses or single-vision spectacles BMJ Open Ophthalmology 2018;3:e000204 is available at http://dx.doi.org/10.1136/bmjophth-2018-000204
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