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Title: | Effects of age, education and gender in the Consortium to Establish a Registry for the Alzheimer's Disease (CERAD)-Neuropsychological Assessment Battery for Cantonese-speaking Chinese elders | Authors: | Liu, KPY Kuo, MCC Tang, KC Chau, AWS Ho, IHT Kwok, MPH Chan, WCW Choi, RHK Lam, NCW Chu, MML Chu, LW |
Issue Date: | Dec-2011 | Source: | International Psychogeriatrics, Dec. 2011, v. 23, no. 10, p. 1575-1581 | Abstract: | Background: The Consortium to Establish a Registry for Alzheimer's Disease Neuropsychological Assessment Battery (CERAD-NAB) offers information on the clinical diagnosis of Alzheimer's disease (AD) and gives a profile of cognitive functioning. This study explores the effects of age, education and gender on participants' performance on eight subtests in the Chinese-Cantonese version of the CERAD-NAB. Methods: The original English version of the CERAD-NAB was translated and content-validated into a Chinese-Cantonese version to suit the Hong Kong Chinese population. The battery was administered to 187 healthy volunteers aged 60 to 94 years. Participants were excluded if they had neurological, medical or psychiatric disorders (including dementia). Stepwise multiple linear regression analyses were performed to assess the relative contribution of the demographic variables to the scores on each subtest. Results: The Cantonese version of CERAD-NAB was shown to have good content validity and excellent inter-rater reliability. Stepwise multiple regression analyses revealed that performances on seven and four out of eight subtests in the CERAD-NAB were significantly influenced by education level and age, respectively. Age and education had significant effects on participants' performance on many tests. Gender also showed a significant effect on one subtest. Conclusions: The preliminary data will serve as an initial phase for clinical interpretation of the CERAD-NAB for Cantonese-speaking Chinese elders. |
Keywords: | Cognitive profile Validation Alzheimer's disease Chinese elders |
Publisher: | Cambridge University Press published on behalf of the International Psychogeriatric Association | Journal: | International Psychogeriatrics | ISSN: | 1041-6102 1741-203X (EISSN) |
DOI: | 10.1017/S1041610211001153 | Rights: | © International Psychogeriatric Association 2011 The follow article "Karen P. Y. Liu, Michael C. C. Kuo, Kin-chung Tang, Allison W. S. Chau, Iris H. T. Ho, Matthew P. H. Kwok, Wallis C. W. Chan, Roy H. K. Choi, Natalie C. W. Lam, Mary M. L. Chu and Leung-wing Chu (2011). Effects of age, education and gender in the Consortium to Establish a Registry for the Alzheimer's Disease (CERAD)-Neuropsychological Assessment Battery for Cantonese-speaking Chinese elders. International Psychogeriatrics, 23(10), pp 1575-1581. doi:10.1017/S1041610211001153." is available at http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=8416590 |
Appears in Collections: | Journal/Magazine Article |
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