Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/40076
Title: 铁调素药物研究现状和应用前景
Authors: 李艳伟
赵晋英
Qian, ZM
Issue Date: 2010
Publisher: 中国学术期刊(光盘版)电子杂志社
Source: 广东医学 (Guangdong medical journal), 2010, v. 31, no. 2, p. 257-260 How to cite?
Journal: 广东医学 (Guangdong medical journal) 
Abstract: 铁代谢紊乱性疾病影响着数以亿计人 口,最为人们所熟知的是,铁缺乏可引起缺铁性贫血,而铁过多将导致血色素沉着症。近年来研究表明铁代谢紊乱造成的危害并不局限于此,机体多种疾病的发生与 铁过载有关,如神经退行性疾病[1]、铁源性心脏病[2]和肝纤维化[3]等。原因是过量的铁可促发大量自由基产生,引起组织损伤。临床常采用放血疗法或 给予去铁敏等铁螯合剂治疗,然而长期跟踪显示此种疗法并不能从根本上治疗铁过载性疾病,且副作用很大[4]。因此,寻找和开发治疗铁过载疾病的有效新药成 为一项刻不容缓的任务。2001年,Park和P igeon等同时发现了一种铁负性调节激素———铁调素(hepc id in,Hepc), 
URI: http://hdl.handle.net/10397/40076
ISSN: 1001-9448
Rights: © 2010 China Academic Journal Electronic Publishing House. It is to be used strictly for educational and research use.
© 2010 中国学术期刊电子杂志出版社。本内容的使用仅限于教育、科研之目的。
Appears in Collections:Journal/Magazine Article

Files in This Item:
File Description SizeFormat 
r46899.pdf281.69 kBAdobe PDFView/Open
Access
View full-text via PolyU eLinks SFX Query
Show full item record
PIRA download icon_1.1View/Download Contents

Page view(s)

41
Last Week
0
Last month
Citations as of Aug 13, 2018

Download(s)

22
Citations as of Aug 13, 2018

Google ScholarTM

Check


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.