Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/91671
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dc.contributorSchool of Nursingen_US
dc.creatorYeung, WFen_US
dc.creatorYu, BYMen_US
dc.creatorYuen, JWMen_US
dc.creatorHo, JYSen_US
dc.creatorChung, KFen_US
dc.creatorZhang, ZJen_US
dc.creatorMak, DSYen_US
dc.creatorSuen, LKPen_US
dc.creatorHo, LMen_US
dc.date.accessioned2021-11-24T06:07:33Z-
dc.date.available2021-11-24T06:07:33Z-
dc.identifier.urihttp://hdl.handle.net/10397/91671-
dc.language.isoenen_US
dc.publisherDove Medical Pressen_US
dc.rights© 2021 Yeung et al. This work is published and licensed by Dove Medical Press Limited.en_US
dc.rightsThe full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).en_US
dc.rightsThe following publication Yeung, W. F., Yu, B. Y. M., Yuen, J. W. M., Ho, J. Y. S., Chung, K. F., Zhang, Z. J., ... & Ho, L. M. (2021). Semi-individualized acupuncture for insomnia disorder and oxidative stress: a randomized, double-Blind, sham-controlled trial. Nature and Science of Sleep, 13, 1195-1207 is available at https://doi.org/10.2147/NSS.S318874en_US
dc.subjectSleepen_US
dc.subjectElectroacupunctureen_US
dc.subjectOxidative stressen_US
dc.subjectPlaceboen_US
dc.subjectChinese medicineen_US
dc.subjectAcupointsen_US
dc.titleSemi-individualized acupuncture for insomnia disorder and oxidative stress : a randomized, double-blind, sham-controlled trialen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage1195en_US
dc.identifier.epage1207en_US
dc.identifier.volume13en_US
dc.identifier.doi10.2147/NSS.S318874en_US
dcterms.abstractBackground: Acupuncture is an alternative treatment for improving sleep, and it may attenuate oxidative stress, which is a possible pathophysiological factor in insomnia. The aim of this study was to examine the efficacy and safety of a semi-individualized acupuncture in improving sleep and explore its effect on oxidative stress parameters in adults with insomnia disorder.en_US
dcterms.abstractMethods: In this randomized sham-controlled trial, 140 participants were randomly assigned to either a 4-week semi-individualized traditional acupuncture (TA) or noninvasive sham acupuncture (SA). The primary outcome measure was the sleep-diary-derived sleep efficiency. Other outcomes included sleep diary and actigraphy, Insomnia Severity Index, anxiety and depressive symptoms, and quality of life. Blood samples were taken to measure oxidative stress parameters (malondialdehyde, glutathione peroxidase, paraoxonase, and arylesterase).en_US
dcterms.abstractResults: Although no significant difference was found in the primary outcome measure, both sleep-diary-derived and actigraphy-derived total sleep time (TST) were significantly increased in the TA group at 1-week posttreatment (mean difference in sleep diary = 22.0 min, p = 0.01, actigraphy = 18.8 min, p = 0.02). At 5-week posttreatment follow-up, a significantly higher proportion of participants in the TA group showed sleep-diary-derived sleep efficiency (SE) >= 85% than in the SA group (55.6% versus 36.4%, p = 0.03).en_US
dcterms.abstractConclusion: TA and SA did not significantly differ in improving subjective sleep efficiency in individuals with insomnia disorder. However, the TA group showed a short-term effect on improving TST as measured by both sleep diary and actigraphy at 1-week posttreatment, but there were no differences in the oxidative stress parameters.en_US
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationNature and science of sleep, 2021, v. 13, p. 1195-1207en_US
dcterms.isPartOfNature and science of sleepen_US
dcterms.issued2021-
dc.identifier.isiWOS:000675822400001-
dc.identifier.pmid34321944-
dc.identifier.eissn1179-1608en_US
dc.description.validate202111 bchyen_US
dc.description.oaVersion of Recorden_US
dc.identifier.FolderNumberRGC-B1-055, OA_Scopus/WOS, a1425-
dc.identifier.SubFormID44945-
dc.description.fundingSourceRGCen_US
dc.description.pubStatusPublisheden_US
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