Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/91401
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dc.contributorDepartment of Electronic and Information Engineering-
dc.creatorLuo, Y-
dc.creatorChu, CH-
dc.creatorVyas, S-
dc.creatorKuo, HY-
dc.creatorChia, YH-
dc.creatorChen, MK-
dc.creatorShi, X-
dc.creatorTanaka, T-
dc.creatorMisawa, H-
dc.creatorHuang, YY-
dc.creatorTsai, DP-
dc.date.accessioned2021-11-03T06:53:21Z-
dc.date.available2021-11-03T06:53:21Z-
dc.identifier.issn1530-6984-
dc.identifier.urihttp://hdl.handle.net/10397/91401-
dc.language.isoenen_US
dc.publisherAmerican Chemical Societyen_US
dc.rights© 2021 The Authors. Published by American Chemical Societyen_US
dc.rightsThis is an open access article under the CC BY-NC-ND license (https://creativecommons.org/licenses/by-nc-nd/4.0/)en_US
dc.rightsThe following publication Luo, Y., Chu, C. H., Vyas, S., Kuo, H. Y., Chia, Y. H., Chen, M. K., ... & Tsai, D. P. (2021). Varifocal Metalens for Optical Sectioning Fluorescence Microscopy. Nano Letters is available at https://doi.org/10.1021/acs.nanolett.1c01114en_US
dc.subjectFluorescence microscopyen_US
dc.subjectHiLo imagingen_US
dc.subjectMetasurfaceen_US
dc.subjectOptical sectioningen_US
dc.subjectTelecentric configurationen_US
dc.titleVarifocal metalens for optical sectioning fluorescence microscopyen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage5133-
dc.identifier.epage5142-
dc.identifier.volume21-
dc.identifier.issue12-
dc.identifier.doi10.1021/acs.nanolett.1c01114-
dcterms.abstractFluorescence microscopy with optical sectioning capabilities is extensively utilized in biological research to obtain three-dimensional structural images of volumetric samples. Tunable lenses have been applied in microscopy for axial scanning to acquire multiplane images. However, images acquired by conventional tunable lenses suffer from spherical aberration and distortions. Here, we design, fabricate, and implement a dielectric Moiré metalens for fluorescence imaging. The Moiré metalens consists of two complementary phase metasurfaces, with variable focal length, ranging from ∼10 to ∼125 mm at 532 nm by tuning mutual angles. In addition, a telecentric configuration using the Moiré metalens is designed for high-contrast multiplane fluorescence imaging. The performance of our system is evaluated by optically sectioned images obtained from HiLo illumination of fluorescently labeled beads, as well as ex vivo mice intestine tissue samples. The compact design of the varifocal metalens may find important applications in fluorescence microscopy and endoscopy for clinical purposes.-
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationNano letters, 23 June 2021, v. 21, no. 12, p. 5133-5142-
dcterms.isPartOfNano letters-
dcterms.issued2021-06-
dc.identifier.scopus2-s2.0-85108642300-
dc.identifier.eissn1530-6992-
dc.description.validate202110 bcvc-
dc.description.oaVersion of Recorden_US
dc.identifier.FolderNumberOA_Scopus/WOSen_US
dc.description.pubStatusPublisheden_US
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