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Title: Attitudes toward COVID-19 vaccines in Chinese college students
Authors: Bai, W
Cai, H
Liu, S
Liu, H
Qi, H
Chen, X
Liu, R
Cheung, T 
Su, Z
Ng, CH
Xiang, YT
Issue Date: 2021
Source: International journal of biological sciences, 2021, v. 17, no. 6, p. 1469-1475
Abstract: Background: Vaccination is an important preventative measure against the coronavirus disease 19 (COVID-19) pandemic. To implement vaccination and immunization programs effectively, it is essential to investigate public attitudes toward COVID-19 vaccines. This study examined the attitudes of Chinese college students toward COVID-19 vaccines and their associated factors.
Methods: A cross-sectional study was conducted in college students nationwide from December 27, 2020 to January 18, 2021. Attitudes toward COVID-19 vaccines and acceptance of future vaccination programs were assessed.
Results: Totally, 2,881 college students participated in this survey; of them, 76.3% (95% CI: 74.8%-77.9%) were willing to accept a COVID-19 vaccine in the future. Multiple logistic analysis revealed that students living in urban (OR=1.409, 95% CI: 1.152 – 1.724, p=0.001) and those studying health-related courses (OR=1.581, 95% CI: 1.291 – 1.935, p<0.001) were more likely to have a positive attitude toward COVID-19 vaccines. In addition, those who were worried about being infected with COVID-19 (very much vs no, OR=1.690, 95% CI: 1.212-2.356, p=0.002), heard previously about COVID-19 vaccines (OR=1.659, 95% CI: 1.268-2.170, p<0.001), believed that vaccines are safe (Yes vs No, OR=3.570, 95% CI: 1.825-6.980), thought that vaccines can protect people from being infected with COVID-19 (Yes vs No, OR=1.957, 95% CI: 1.286-2.979, p=0.002), and had encouraged their family and friends to have a vaccine (Yes vs No, OR=17.745, 95% CI: 12.271-25.660, p<0.001) had higher acceptance of COVID-19 vaccination.
Conclusions: A high rate of acceptance of COVID-19 vaccines was found among Chinese college students. However, vaccine uptake may be reduced by concerns about vaccine safety and efficacy. Alleviating these concerns and enhancing public confidence in vaccines are crucial for future immunization programs against the COVID-19 pandemic.
Keywords: Attitude
College students
Coronavirus disease 19
Publisher: Ivyspring International Publisher
Journal: International journal of biological sciences 
EISSN: 1449-2288
DOI: 10.7150/ijbs.58835
Rights: © The author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License ( See for full terms and conditions.
The following publication Bai W, Cai H, Liu S, Liu H, Qi H, Chen X, Liu R, Cheung T, Su Z, Ng CH, Xiang YT. Attitudes toward COVID-19 vaccines in Chinese college students. Int J Biol Sci 2021; 17(6):1469-1475 is available at
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