Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/90261
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dc.contributorSchool of Optometryen_US
dc.creatorBanerjee, Sen_US
dc.creatorWang, Qen_US
dc.creatorTang, Gen_US
dc.creatorSo, Cen_US
dc.creatorShan, SWen_US
dc.creatorLi, KKen_US
dc.creatorDo, CWen_US
dc.creatorPan, Fen_US
dc.date.accessioned2021-06-02T01:33:29Z-
dc.date.available2021-06-02T01:33:29Z-
dc.identifier.issn0952-5238en_US
dc.identifier.urihttp://hdl.handle.net/10397/90261-
dc.descriptionCorrection appeared in: Banerjee, S., Wang, Q., Tang, G., So, C., Shan, S., Li, K., . . . Pan, F. (2021). Functional connexin35 increased in the myopic chicken retina—CORRIGENDUM. Visual Neuroscience, 38, E009. doi:10.1017/S0952523821000109en_US
dc.descriptionhttps://ira.lib.polyu.edu.hk/handle/10397/95443en_US
dc.descriptionPlease note a correction has been issued for this article.en_US
dc.descriptionIn the original version of Banerjee et al., Reference Banerjee, Wang, Tang, So, Shan, Li, Do and Pan2021, author Qin Wang’s name was misspelled.en_US
dc.language.isoenen_US
dc.publisherCambridge University Pressen_US
dc.rights© School of Optometry, The Hong Kong Polytechnic University, 2021. Published by Cambridge University Press. This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.en_US
dc.rightsThe following publication Banerjee, S., Wang, Q., Tang, G., So, C., Shan, S. W., Li, K. K., ... & Pan, F. (2021). Functional connexin35 increased in the myopic chicken retina. Visual Neuroscience, 38:E008 is available at https://doi.org/10.1017/S0952523821000079en_US
dc.subjectMyopiaen_US
dc.subjectGap junctionen_US
dc.subjectRetinaen_US
dc.subjectAmacrine cellen_US
dc.titleFunctional connexin35 increased in the myopic chicken retinaen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.volume38en_US
dc.identifier.doi10.1017/S0952523821000079en_US
dcterms.abstractOur previous research showed that increased phosphorylation of connexin (Cx)36 indicated extended coupling of AII amacrine cells (ACs) in the rod-dominant mouse myopic retina. This research will determine whether phosphorylation at serine 276 of Cx35-containing gap junctions increased in the myopic chicken, whose retina is cone-dominant. Refractive errors and ocular biometric dimensions of 7-days-old chickens were determined following 12 h and 7 days induction of myopia by a −10D lens. The expression pattern and size of Cx35-positive plaques were examined in the early (12 h) and compensated stages (7 days) of lens-induced myopia (LIM). At the same time, phosphorylation at serine 276 (functional assay) of Cx35 in strata 5 (S5) of the inner plexiform layer was investigated. The axial length of the 7 days LIM eyes was significantly longer than that of non-LIM controls (P < 0.05). Anti-phospho-Ser276 (Ser276-P)-labeled plaques were significantly increased in LIM retinas at both 12 h and 7 days. The density of Ser276-P of Cx35 was observed to increase after 12 h LIM. In the meanwhile, the areas of existing Cx35 plaques did not change. As there was more phosphorylation of connexin35 at Ser276 at both the early and late stages (12 h) and 7 days of LIM chicken retinal activity, the coupling with ACs could be increased in myopia development of the cone-dominated chicken retina.en_US
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationVisual Neuroscience, 2021. v. 38, E008en_US
dcterms.isPartOfVisual Neuroscienceen_US
dcterms.issued2021-
dc.identifier.scopus2-s2.0-85106054449-
dc.identifier.eissn1469-8714en_US
dc.identifier.artnE008en_US
dc.description.validate202106 bcvcen_US
dc.description.oaVersion of Recorden_US
dc.identifier.FolderNumbera0894-n01, a0906-n01-
dc.identifier.SubFormID2098, 2116-
dc.description.fundingSourceRGCen_US
dc.description.fundingSourceOthersen_US
dc.description.fundingTextRGC: 25103918en_US
dc.description.pubStatusPublisheden_US
dc.description.TACUP (2021)en_US
dc.description.oaCategoryTAen_US
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