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| Title: | One‐year results of the Variation of Orthokeratology Lens Treatment Zone (VOLTZ) study : a prospective randomised clinical trial | Authors: | Guo, B Cheung, SW Kojima, R Cho, P |
Issue Date: | Jul-2021 | Source: | Ophthalmic and physiological optics, July 2021, v. 41, no. 4, p. 702-714 | Abstract: | Purpose: To present the 1-year results of the Variation of Orthokeratology LensTreatment Zone (VOLTZ) Study, which aims to investigate the myopia controleffect of orthokeratology (ortho-k) lenses with different back optic zone diameters(BOZD). Method: Children, aged 6 to <11 years, having myopia −4.00 D to −0.75D, were randomly assigned to wear ortho-k lenses with 6 mm (6-MM group) or5 mm (5-MM group) BOZD. Data collection included changes in refraction,vision, lens performance and binding, ocular health conditions, axial length andcharacteristics of the treatment zone (TZ) area. Results: The 1-year results of 34 and 36 subjects (right eye only) in the 6-MMand 5-MM groups, respectively, are presented. No significant differences in base-line demographics were found between the groups (p > 0.05). The first-fit successrates, based on satisfactory centration at the 1-month visit, were 100% and 94%respectively. Horizontal TZ size was 0.92 mm and 0.72 mm smaller in the 5-MMgroup at the 6-month and 12-month visits, respectively (p < 0.05). At the 12-month visit, no significant between-group differences were found in the incidenceof corneal staining (low grade only), lens binding and visual performance (allp > 0.05). Axial elongation was slower in the 5-MM group (0.04 0.15 mm)than the 6-MM group (0.17 0.13 mm) (p = 0.001). A significant positive cor-relation was observed between the horizontal TZ size and axial elongation(r = 0.36, p = 0.006). Conclusion: Clinical performance of the two ortho-k lenses was similar, indicat-ing that a smaller BOZD (5 mm) did not affect lens performance or ocular integ-rity. However, a smaller BOZD led to a reduced TZ, with retardation of axialelongation by 0.13 mm compared to conventional 6 mm BOZD ortho-k lensesafter one year of lens wear. |
Keywords: | BOZD Myopia control Orthokeratology Treatment zone |
Publisher: | Wiley-Blackwell | Journal: | Ophthalmic and physiological optics | ISSN: | 0275-5408 | EISSN: | 1475-1313 | DOI: | 10.1111/opo.12834 | Rights: | © 2021 The Authors. Ophthalmic and Physiological Optics published by John Wiley & Sons Ltd on behalf of College of Optometrists. This is an open access article under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits use, distribution and reproduction in any medium, provided the original work is properly cited. The following publication Guo, B, Cheung, SW, Kojima, R, & Cho, P. One-year results of the Variation of Orthokeratology Lens Treatment Zone (VOLTZ) Study: a prospective randomised clinical trial. Ophthalmic Physiol Opt 2021; 41: 702– 714 is available at https://doi.org/10.1111/opo.12834 |
| Appears in Collections: | Journal/Magazine Article |
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| opo.12834.pdf | 4.44 MB | Adobe PDF | View/Open |
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