Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/89674
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dc.contributorDepartment of Rehabilitation Sciences-
dc.contributorDepartment of Health Technology and Informatics-
dc.creatorKannan, Pen_US
dc.creatorCheung, KKen_US
dc.creatorChan, SCen_US
dc.creatorLam, KYen_US
dc.creatorLaw, YXen_US
dc.creatorNg, SKen_US
dc.creatorSiu, HYen_US
dc.creatorWong, SCen_US
dc.date.accessioned2021-04-28T02:29:07Z-
dc.date.available2021-04-28T02:29:07Z-
dc.identifier.urihttp://hdl.handle.net/10397/89674-
dc.language.isoenen_US
dc.publisheriMedPuben_US
dc.rights© Copyright iMedPub.This article is available in: http://biomarkers.imedpub.com/archive.phpen_US
dc.rights© Under License of Creative Commons Attribution 3.0 Licensen_US
dc.rightsThe following publication Kannan P, Cheung KK, Chi CS, Yan LK, Xi LY, et al. (2020) Effect of Aerobic Exercise on Plasma Biomarkers of Pain in Women with Primary Dysmenorrhea: A Controlled Non-randomized Pilot Trial. Biomark J. Vol. 6 No. 2: 67. is available at https://doi.org/10.36648/2472-1646.6.2.67.en_US
dc.subjectAerobic exerciseen_US
dc.subjectBiomarkersen_US
dc.subjectPainen_US
dc.subjectPrimary dysmenorrheaen_US
dc.subjectProgesteroneen_US
dc.subjectProstaglandinsen_US
dc.titleEffect of aerobic exercise on plasma biomarkers of pain in women with primary dysmenorrhea : a controlled non-randomized pilot trialen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage1en_US
dc.identifier.epage9en_US
dc.identifier.volume6en_US
dc.identifier.issue2en_US
dc.identifier.doi10.36648/2472-1646.6.2.67en_US
dcterms.abstractObjectives: To (1) evaluate preliminary effects of aerobic exercise on progesterone, prostaglandin metabolites and pro-inflammatory cytokines in women with primary dysmenorrhea, (2) assess the feasibility of methodological procedures and obtain preliminary data (effect size) to estimate the sample size for a future randomized controlled trial.-
dcterms.abstractMethods: Twenty women aged 18-29 years were divided into two groups (highintensity aerobic-exercise group and no-exercise control group) in a 1:1 ratio. Women assigned to the exercise group performed high-intensity treadmillbased aerobic exercise for three days a week, at 70-85% of maximum heart rate for 30 minutes for 4 weeks. The control group did not receive trial intervention but provided blood for estimation of plasma variables. Blood plasma levels of progesterone, prostaglandin (PG) metabolites, F2 alpha [KDPGF2α]) and PGE2 (KDPGE2), and tumor necrosis factor-alpha (TNF-α) were measured at 4-weeks post-intervention.-
dcterms.abstractResults: There was an increase in progesterone levels (d=0.36) and decreases in KDPGF2α (d=0.35), KDPGE2 (d= 0.47), and TNF-α (d=0.33) from baseline to week 4 in the exercise group compared with the control group. Concerning feasibility outcomes, 90% of the required number of participants were recruited in 3-4 weeks and adherence to the intervention was 97%.-
dcterms.abstractConclusion: Study findings suggest that aerobic exercise may be effective for primary dysmenorrhea via its influence on progesterone and inflammatory pain mediators. The study methodology appears to be feasible for conducting a fullscale randomized controlled trial.-
dcterms.accessRightsopen access-
dcterms.bibliographicCitationBiomarkers journal, 2020, v. 6, no. 2, 67, p. 1-9en_US
dcterms.isPartOfBiomarkers journalen_US
dcterms.issued2020-
dc.identifier.eissn2472-1646en_US
dc.identifier.artn67en_US
dc.description.validate202104 bcvc-
dc.description.oaVersion of Record-
dc.identifier.FolderNumbera0771-n01, a0657-n04-
dc.identifier.SubFormID1544, 755-
dc.description.fundingSourceOthers-
dc.description.fundingTextStart-up fund (1-ZE8G) provided for early-career academics by the Hong Kong Polytechnic University-
dc.description.pubStatusPublished-
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