Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/89396
| Title: | Effect of povidone iodine contact lens disinfecting solution on orthokeratology lens and lens case contamination and organisms in the microbiome of the conjunctiva | Authors: | Cheung, SW Boost, MV Cho, P |
Issue Date: | Dec-2021 | Source: | Contact lens and anterior eye, Dec. 2021, v. 44, no. 6, 101412 | Abstract: | Purpose: To compare lens cleaning routines using a povidone iodine-based rigid lens disinfecting solution and its effect on conjunctival colonisation, and lens and lens case contamination. Methods:Participants, aged 6–10 years, receiving orthokeratology treatment were randomised to four lens cleaning routines: with and without the use of daily and/or weekly cleaners, which were performed by their parents. Conjunctival colonisation was compared before lens wear and at 1-, 3-, and 6-month after commencement of lens wear. Contamination of lenses and lens cases was investigated at these times. Organisms were identified using MALDI-TOF mass spectrometry. Results: Of the 76 participants who completed the study, conjunctival colonization was present in 24 (32 %) at baseline. Of the remaining 52 participants, 34 consistently yielded no growth. Participants positive at baseline were statistically more likely to be colonized after commencement of lens wear (p = 0.020). Overall, colonization rate was reduced to 15 % (11/72) after 6-month lens wear, which reached significance for initially colonized participants (p < 0.001). Few cultures yielded potential ocular pathogens, with notably no Pseudomonas aeruginosa. Contamination rates of both lenses and lens cases were also low, with few isolations of ocular pathogens. No significant differences were observed between cleaning regimes for conjunctival colonization or contamination of lenses or cases. Conclusions: Disinfection for rigid and ortho-k lens wearers may be effectively achieved with the use of povidone iodine-based solution, apparently regardless of cleaning routine adopted in the current study. The absence of pathogens in the conjunctiva, lenses, and lens cases in the great majority of samples indicates that it can improve the safety of overnight lens wear. |
Keywords: | Povidone iodine Contamination Colonisation Lens case Orthokeratology |
Publisher: | Elsevier | Journal: | Contact lens and anterior eye | ISSN: | 1367-0484 | EISSN: | 1476-5411 | DOI: | 10.1016/j.clae.2021.01.007 | Rights: | © 2021 British Contact Lens Association. Published by Elsevier Ltd. All rights reserved © 2021. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/. The following publication Cheung, S. W., Boost, M. V., & Cho, P. (2021). Effect of povidone iodine contact lens disinfecting solution on orthokeratology lens and lens case contamination and organisms in the microbiome of the conjunctiva. Contact Lens and Anterior Eye, 44(6), 101412 is available at https://dx.doi.org/10.1016/j.clae.2021.01.007. |
| Appears in Collections: | Journal/Magazine Article |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Cheung_Povidone_Iodine_Contact.pdf | Pre-Published version | 1.44 MB | Adobe PDF | View/Open |
Access
View full-text via PolyU eLinks 
Page views
20
Last Week
0
0
Last month
Citations as of Jun 4, 2023
Downloads
2
Citations as of Jun 4, 2023
SCOPUSTM
Citations
4
Citations as of Jun 2, 2023
WEB OF SCIENCETM
Citations
3
Citations as of Jun 1, 2023
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.