Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/89206
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dc.contributorSchool of Optometryen_US
dc.creatorCho, Pen_US
dc.creatorCheung, SWen_US
dc.creatorBoost, MVen_US
dc.date.accessioned2021-02-18T09:14:42Z-
dc.date.available2021-02-18T09:14:42Z-
dc.identifier.urihttp://hdl.handle.net/10397/89206-
dc.language.isoenen_US
dc.publisherPublic Library of Scienceen_US
dc.rights© 2020 Cho et al. This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.en_US
dc.rightsThe following publication Cho P, Cheung SW, Boost MV (2020) Categorisation of myopia progression by change in refractive error and axial elongation and their impact on benefit of myopia control using orthokeratology. PLoS ONE 15(12): e0243416 is available at https://doi.org/10.1371/journal.pone.0243416en_US
dc.titleCategorisation of myopia progression by change in refractive error and axial elongation and their impact on benefit of myopia control using orthokeratologyen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.volume15en_US
dc.identifier.issue12en_US
dc.identifier.doi10.1371/journal.pone.0243416en_US
dcterms.abstractAims: To compare the value of pre-treatment axial elongation (AE) and changes in refractive sphere (M change) for predicting the success in orthokeratology (ortho-k), in order to better identify suitable candidates for myopia control.en_US
dcterms.abstractMethods: This study further analysed the data of 66 subjects receiving 7-month ortho-k treatment, following a 7-month observation period, during which single-vision spectacles were worn. Rate of myopia progression was determined by AE and M change and subjects categorised as slow, moderate, or rapid progressors based on these changes. Outcomes of myopia control, based on the AE reduction after ortho-k, were classified as ‘ineffectual’, ‘clinically insignificant’, or ‘beneficial’.en_US
dcterms.abstractResults: Of the 20 subjects, initially categorised as slow by AE and, of whom 95% were similarly categorised by M change, none benefitted from ortho-k. In contrast, of the 22 subjects with moderate AE, 77% and 23% displaying slow and moderate M change, respectively, the majority (73%) benefitted from ortho-k lens wear. The 24 subjects with rapid AE were poorly identified by M change, with only 21% correctly categorised. The vast majority of rapid progressors showed significant benefit after ortho-k.en_US
dcterms.abstractConclusion: Progression of AE is a good indicator of subsequent success of ortho-k treatment. Delaying commencement of therapy is prudent for children with slow progression as results indicate that they would be unlikely to benefit from this intervention. As change in refractive error frequently underestimates rapid progression of AE, its value for identifying appropriate candidates for myopia control is poor.en_US
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationPLoS one, 29 Dec. 2020, v. 15, no. 12, e0243416en_US
dcterms.isPartOfPLoS oneen_US
dcterms.issued2020-12-29-
dc.identifier.scopus2-s2.0-85098967336-
dc.identifier.pmid33373370-
dc.identifier.eissn1932-6203en_US
dc.identifier.artne0243416en_US
dc.description.validate202102 bcwhen_US
dc.description.oaVersion of Recorden_US
dc.identifier.FolderNumbera0581-n01-
dc.description.fundingSourceOthersen_US
dc.description.fundingTextThis study was supported by Collaborative Research Agreements between PolyU and Menicon Co. Ltd, Japan (Pauline Cho; ZG50, ZG7X)en_US
dc.description.pubStatusPublisheden_US
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