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http://hdl.handle.net/10397/88443
| Title: | A small-sized benzothiazole–indolium fluorescentprobe: the study of interaction specificitytargeting c-MYC promoter G-quadruplexstructures and live cell imaging | Authors: | Zheng, BX She, MT Long, W Xu, YY Zhang, YH Huang, XH Liu, W Hou, JQ Wong,WL Lu, YJ |
Issue Date: | 2020 | Source: | Chemical communications, 2020, v. 56, no. 100, p. 15016-15019 | Abstract: | A small-sized c-MYC promoter G-quadruplex selective fluorescentBZT-Indolium binding ligand was demonstrated for the first time as ahighly target-specific and photostable probe forin vitrostaining andlive cell imaging and it was found to beable to inhibit the amplificationof the c-MYC G-rich sequence (G-quadruplex) and down-regulateoncogene c-MYC expression inhuman cancer cells (HeLa) | Publisher: | Royal Society of Chemistry | Journal: | Chemical communications | ISSN: | 1359-7345 | EISSN: | 1364-548X | DOI: | 10.1039/d0cc06525k | Rights: | This journal is © The Royal Society of Chemistry 2020 The following publication Zheng, B.-X., She, M.-T., Long, W., Xu, Y.-Y., Zhang, Y.-H., Huang, X.-H., Liu, W., Hou, J.-Q., Wong, W.-L., & Lu, Y.-J. (2020). A small-sized benzothiazole–indolium fluorescent probe: the study of interaction specificity targeting c-MYC promoter G-quadruplex structures and live cell imaging [10.1039/D0CC06525K]. Chemical Communications, 56(95), 15016-15019. https://doi.org/10.1039/D0CC06525K is available at https://dx.doi.org/10.1039/d0cc06525k. |
| Appears in Collections: | Journal/Magazine Article |
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| Zheng_Small-sized_Benzothiazole-indolium_Fluorescent.pdf | Pre-Published version | 5.39 MB | Adobe PDF | View/Open |
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