Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/88442
| Title: | New applications of oleanolic acid and its derivatives as cardioprotective agents : a review of their therapeutic perspectives | Authors: | Sun, N Li, D Chen, X Wu, P Lu, YJ Hou, N Chen, WH Wong, WL |
Issue Date: | 2019 | Source: | Current pharmaceutical design, 2019, v. 25, no. 35, p. 3740-3750 | Abstract: | Oleanolic acid is an analogue of pentacyclic triterpenoids. It has been used as a hepatic drug for over 20 years in China. Currently, there are only five approved drugs derived from pentacyclic triterpenoids, including oleanolic acid (liver diseases), asiaticoside (wound healing), glycyrrhizinate (liver diseases), isoglycyrrhizinate (liver disease) and sodium aescinate (hydrocephalus). To understand more about the bioactivity and functional mechanisms of oleanolic acid, it can be developed as a potent therapeutic agent, in particular, for the prevention and treatment of heart diseases that are the leading cause of death for people worldwide. The primary aim of this mini-review is to summarize the new applications of oleanolic acid and its derivatives as cardioprotective agents reported in recent years and to highlight their therapeutic perspectives in cardiovascular diseases. | Keywords: | Asiaticoside Cardioprotective agents Cardiovascular diseases Hepatic drug Oleanolic acid Pentacyclic triterpenoids |
Publisher: | Bentham Science Publishers | Journal: | Current pharmaceutical design | ISSN: | 1381-6128 | DOI: | 10.2174/1381612825666191105112802 | Rights: | © Bentham Science Publishers Ning Sun , Dongli Li , Xiaoqing Chen, Panpan Wu , Yu-Jing Lu , Ning Hou, Wen-Hua Chen and Wing-Leung Wong, “New Applications of Oleanolic Acid and its Derivatives as Cardioprotective Agents: A Review of their Therapeutic Perspectives”, Current Pharmaceutical Design (2019) 25: 3740||The published manuscript is available at EurekaSelect via http://www.eurekaselect.com/openurl/content.php?genre=article&doi=10.2174/1381612825666191105112802. |
| Appears in Collections: | Journal/Magazine Article |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| a0505-n04.pdf | Pre-Published version | 987.54 kB | Adobe PDF | View/Open |
Access
View full-text via PolyU eLinks 
Page views
54
Last Week
2
2
Last month
Citations as of Jun 4, 2023
Downloads
42
Citations as of Jun 4, 2023
SCOPUSTM
Citations
10
Citations as of Jun 8, 2023
WEB OF SCIENCETM
Citations
11
Citations as of Jun 8, 2023
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.