Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/88169
DC Field | Value | Language |
---|---|---|
dc.contributor | Institute of Textiles and Clothing | - |
dc.creator | Yan, K | - |
dc.creator | Zhang, YB | - |
dc.creator | Mu, CL | - |
dc.creator | Xu, QN | - |
dc.creator | Jing, XA | - |
dc.creator | Wang, DQ | - |
dc.creator | Dang, DF | - |
dc.creator | Meng, LJ | - |
dc.creator | Ma, JZ | - |
dc.date.accessioned | 2020-09-18T02:13:23Z | - |
dc.date.available | 2020-09-18T02:13:23Z | - |
dc.identifier.uri | http://hdl.handle.net/10397/88169 | - |
dc.language.iso | en | en_US |
dc.publisher | Ivyspring International Publisher | en_US |
dc.rights | © The author(s). This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/).See http://ivyspring.com/terms for full terms and conditions. | en_US |
dc.rights | The following publication Yan K, Zhang Y, Mu C, Xu Q, Jing X, Wang D, Dang D, Meng L, Ma J. Versatile Nanoplatforms with enhanced Photodynamic Therapy: Designs and Applications. Theranostics 2020; 10(16):7287-7318 is available at https://dx.doi.org/10.7150/thno.46288 | en_US |
dc.subject | Photodynamic therapy | en_US |
dc.subject | Malignant tumor | en_US |
dc.subject | Versatile nanoplatforms | en_US |
dc.subject | Microenvironment | en_US |
dc.title | Versatile nanoplatforms with enhanced photodynamic therapy : designs and applications | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.spage | 7287 | - |
dc.identifier.epage | 7318 | - |
dc.identifier.volume | 10 | - |
dc.identifier.issue | 16 | - |
dc.identifier.doi | 10.7150/thno.46288 | - |
dcterms.abstract | As an emerging antitumor strategy, photodynamic therapy (PDT) has attracted intensive attention for the treatment of various malignant tumors owing to its noninvasive nature and high spatial selectivity in recent years. However, the therapeutic effect is unsatisfactory on some occasions due to the presence of some unfavorable factors including nonspecific accumulation of PS towards malignant tissues, the lack of endogenous oxygen in tumors, as well as the limited light penetration depth, further hampering practical application. To circumvent these limitations and improve real utilization efficiency, various enhanced strategies have been developed and explored during the past years. In this review, we give an overview of the state-of-the-art advances progress on versatile nanoplatforms for enhanced PDT considering the enhancement from targeting or responsive, chemical and physical effect. Specifically, these effects mainly include organelle-targeting function, tumor microenvironment responsive release photosensitizers (PS), self-sufficient O-2 (affinity oxygen and generating oxygen), photocatalytic water splitting, X-rays light stimulate, surface plasmon resonance enhancement, and the improvement by resonance energy transfer. When utilizing these strategies to improve the therapeutic effect, the advantages and limitations are addressed. Finally, the challenges and prospective will be discussed and demonstrated for the future development of advanced PDT with enhanced efficacy. | - |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Theranostics, 2020, v. 10, no. 16, p. 7287-7318 | - |
dcterms.isPartOf | Theranostics | - |
dcterms.issued | 2020 | - |
dc.identifier.isi | WOS:000545974400004 | - |
dc.identifier.pmid | 32641993 | - |
dc.identifier.eissn | 1838-7640 | - |
dc.description.validate | 202009 bcrc | - |
dc.description.oa | Version of Record | en_US |
dc.identifier.FolderNumber | OA_Scopus/WOS | en_US |
dc.description.pubStatus | Published | en_US |
dc.description.oaCategory | CC | en_US |
Appears in Collections: | Journal/Magazine Article |
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File | Description | Size | Format | |
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Yan_Versatile_Nanoplatforms_Photodynamic.pdf | 5.46 MB | Adobe PDF | View/Open |
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