Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/81650
PIRA download icon_1.1View/Download Full Text
DC FieldValueLanguage
dc.contributorDepartment of Health Technology and Informatics-
dc.creatorIslam, R-
dc.creatorLai, C-
dc.date.accessioned2020-02-10T12:28:25Z-
dc.date.available2020-02-10T12:28:25Z-
dc.identifier.urihttp://hdl.handle.net/10397/81650-
dc.language.isoenen_US
dc.publisherMolecular Diversity Preservation International (MDPI)en_US
dc.rights© 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).en_US
dc.rightsThe following publication Islam, R.; Lai, C. A Brief Overview of lncRNAs in Endothelial Dysfunction-Associated Diseases: From Discovery to Characterization. Epigenomes 2019, 3, 20, 1-33 is available at https://dx.doi.org/10.3390/epigenomes3030020en_US
dc.subjectEndothelial dysfunctionen_US
dc.subjectLncRNAsen_US
dc.subjectAngiogenesisen_US
dc.subjectHypertensionen_US
dc.subjectAtherosclerosisen_US
dc.subjectDiabetesen_US
dc.titleA brief overview of lncRNAs in endothelial dysfunction-associated diseases : from discovery to characterizationen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage1-
dc.identifier.epage33-
dc.identifier.volume3-
dc.identifier.issue3-
dc.identifier.doi10.3390/epigenomes3030020-
dcterms.abstractLong non-coding RNAs (lncRNAs) are a novel class of regulatory RNA molecules and they are involved in many biological processes and disease developments. Several unique features of lncRNAs have been identified, such as tissue-and/or cell-specific expression pattern, which suggest that they could be potential candidates for therapeutic and diagnostic applications. More recently, the scope of 1ncRNA studies has been extended to endothelial biology research. Many of lncRNAs were found to be critically involved in the regulation of endothelial function and its associated disease progression. An improved understanding of endothelial biology can thus facilitate the discovery of novel biomarkers and therapeutic targets for endothelial dysfunction-associated diseases, such as abnormal angiogenesis, hypertension, diabetes, and atherosclerosis. Nevertheless, the underlying mechanism of lncRNA remains undefined in previous published studies. Therefore, in this review, we aimed to discuss the current methodologies for discovering and investigating the functions of lncRNAs and, in particular, to address the functions of selected lncRNAs in endothelial dysfunction-associated diseases.-
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationEpigenomes, Sept. 2019, v. 3, no. 3, 20, p. 1-33-
dcterms.isPartOfEpigenomes-
dcterms.issued2019-
dc.identifier.isiWOS:000488110500007-
dc.identifier.eissn2075-4655-
dc.identifier.artn20-
dc.description.validate202002 bcrc-
dc.description.oaVersion of Recorden_US
dc.identifier.FolderNumberOA_Scopus/WOSen_US
dc.description.pubStatusPublisheden_US
Appears in Collections:Journal/Magazine Article
Files in This Item:
File Description SizeFormat 
Islam_LncRNAs_Endothelial_Dysfunction-Associated.pdf1.38 MBAdobe PDFView/Open
Open Access Information
Status open access
File Version Version of Record
Access
View full-text via PolyU eLinks SFX Query
Show simple item record

Page views

60
Last Week
2
Last month
Citations as of Mar 24, 2024

Downloads

56
Citations as of Mar 24, 2024

SCOPUSTM   
Citations

2
Citations as of Mar 22, 2024

WEB OF SCIENCETM
Citations

2
Citations as of Mar 28, 2024

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.