Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/81324
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dc.contributorDepartment of Applied Physics-
dc.creatorDeng, ZM-
dc.creatorJiang, MY-
dc.creatorLi, YB-
dc.creatorLiu, HR-
dc.creatorZeng, SJ-
dc.creatorHao, JH-
dc.date.accessioned2019-09-20T00:55:03Z-
dc.date.available2019-09-20T00:55:03Z-
dc.identifier.urihttp://hdl.handle.net/10397/81324-
dc.language.isoenen_US
dc.publisherCell Pressen_US
dc.rights©2019 The Author(s).en_US
dc.rightsThis is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)en_US
dc.rightsThe following publication Deng, Z. M., Jiang, M. Y., Li, Y. B., Liu, H. R., Zeng, S. J., & Hao, J. H. (2019). Endogenous H2S-Triggered in situ synthesis of NIR-II-Emitting nanoprobe for in vivo intelligently lighting up colorectal cancer. iScience, 17, 217-224 is available at https://dx.doi.org/10.1016/j.isci.2019.06.034en_US
dc.titleEndogenous H2S-Triggered in situ synthesis of NIR-II-Emitting nanoprobe for in vivo intelligently lighting up colorectal canceren_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage217-
dc.identifier.epage224-
dc.identifier.volume17-
dc.identifier.doi10.1016/j.isci.2019.06.034-
dcterms.abstractOverexpression of endogenous H2S is one of the key characteristic in colon cancer. However, developing endogenous H2S-activated optical probes for specific diagnosis of colorectal cancer is rarely explored. Herein, an in situ H2S-activatable second near-infrared (NIR-II)-emitting nanoprobe based on Ag-chicken egg white (Ag-CEW) complex for intelligently lighting up colorectal cancer was explored. The designed Ag-CEW complex holds efficient NIR-II emission of 1,000-1,400 nm via endogenous H2S-induced in situ chemical reaction to form Ag2S quantum dots (QDs). After reaction, the designed Ag-CEW complex with high photo-stability and biocompatibility was successfully used for NIR-II imaging-guided specific visualization and precise location of colorectal cancer via endogenous H2S activation. Therefore, our findings provide a new route for specifically targeting diagnosis of colon cancer based on the in situ-activatable NIR-II probe.-
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationiScience, 26 July 2019, v. 17, p. 217-224-
dcterms.isPartOfiScience-
dcterms.issued2019-
dc.identifier.isiWOS:000477767700018-
dc.identifier.scopus2-s2.0-85068569872-
dc.identifier.pmid31301632-
dc.identifier.eissn2589-0042-
dc.description.validate201909 bcrc-
dc.description.oaVersion of Recorden_US
dc.identifier.FolderNumberOA_Scopus/WOSen_US
dc.description.pubStatusPublisheden_US
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