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http://hdl.handle.net/10397/79625
Title: | The relationships between brain structural changes and perceived loneliness in older adults suffering from late-life depression | Authors: | Sin, ELL Liu, HL Lee, SH Huang, CM Wai, YY Chen, YL Chan, CCH Lin, CM Lee, TMC |
Issue Date: | 2018 | Source: | International journal of geriatric psychiatry, Apr. 2018, v. 33, no. 4, p. 606-612 | Abstract: | Objective Late-life depression is a significant health risk factor for older adults, part of which is perceived loneliness. In this voxel-based morphometry study, we examined the relationships between perceived loneliness and depression recurrence. Methods Fifty-two older adults were recruited, and they were split into 3 groups: single episode, multiple episodes, or normal control groups, according to their clinical histories. Results This result suggests the level of functioning regarding the reward system may be negatively related to the number of depressive episodes. Taken together, the findings of this study offer important insight into the neural underpinnings of the course and chronicity of late-life depression. |
Keywords: | Late-life depression MRI Perceived loneliness Voxel-based morphometry |
Publisher: | John Wiley & Sons | Journal: | International journal of geriatric psychiatry | ISSN: | 0885-6230 | EISSN: | 1099-1166 | DOI: | 10.1002/gps.4831 | Rights: | This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made. © 2017 The Authors. International Journal of Geriatric Psychiatry Published by John Wiley & Sons Ltd. The following publication Sin, E. L. L., Liu, H. L., Lee, S. H., Huang, C. M., Wai, Y. Y., Chen, Y. L., … & Lee, T. M. C. (2018). The relationships between brain structural changes and perceived loneliness in older adults suffering from late-life depression. International Journal of Geriatric Psychiatry, 33(4), 606-612 is available at https://dx.doi.org/10.1002/gps.4831 |
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