Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/77566
PIRA download icon_1.1View/Download Full Text
DC FieldValueLanguage
dc.contributorDepartment of Biomedical Engineeringen_US
dc.creatorZhang, Cen_US
dc.creatorLi, Ten_US
dc.creatorChiu, KYen_US
dc.creatorWen, Cen_US
dc.creatorXu, Aen_US
dc.creatorYan, CHen_US
dc.date.accessioned2018-08-28T01:33:16Z-
dc.date.available2018-08-28T01:33:16Z-
dc.identifier.issn1752-0363en_US
dc.identifier.urihttp://hdl.handle.net/10397/77566-
dc.language.isoenen_US
dc.publisherFuture Medicine Ltd.en_US
dc.rights© 2018 Future Medicine Ltden_US
dc.rightsThis is the peer reviewed version of the following article: Zhang, C., Li, T., Chiu, K. Y., Wen, C., Xu, A., & Yan, C. H. (2018). FABP4 as a biomarker for knee osteoarthritis. Biomarkers in medicine, 12(2), 107-118, which has been published in final form at https://doi.org/10.2217/bmm-2017-0207en_US
dc.subjectFABP4en_US
dc.subjectInfrapatellar fat paden_US
dc.subjectOsteoarthritisen_US
dc.titleFABP4 as a biomarker for knee osteoarthritisen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage107en_US
dc.identifier.epage118en_US
dc.identifier.volume12en_US
dc.identifier.issue2en_US
dc.identifier.doi10.2217/bmm-2017-0207en_US
dcterms.abstractAim: To explore the role of an adipokine-termed fatty acid-binding protein 4 (FABP4) in osteoarthritis (OA). Methods: Patients with primary knee OA and non-OA controls were included. Paired tissues including plasma, synovial fluid (SF), subcutaneous fat and infrapatellar fat pad (IPFP) were harvested during surgery. FABP4 concentration was determined by ELISA. Results: Plasma FABP4 increased significantly with OA stage (n = 263). OA patients (n = 38) had significantly higher plasma and SF FABP4 than non-OA patients (n = 29). FABP4 level of IPFP was positively correlated with SF FABP4. Conclusion: OA patients had significantly high systemic and local FABP4, and IPFP may be the main source of FABP4 in synovial cavity. FABP4 may be a promising biomarker for OA.en_US
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationBiomarkers in medicine, Feb. 2018, v. 12, no. 2, p. 107-118en_US
dcterms.isPartOfBiomarkers in medicineen_US
dcterms.issued2018-02-
dc.identifier.isiWOS:000424013300004-
dc.identifier.scopus2-s2.0-85041399149-
dc.identifier.eissn1752-0371en_US
dc.identifier.rosgroupid2017000557-
dc.description.ros2017-2018 > Academic research: refereed > Publication in refereed journalen_US
dc.description.validate201808 bcrcen_US
dc.description.oaAccepted Manuscripten_US
dc.identifier.FolderNumberBME-0166-
dc.description.fundingSourceOthersen_US
dc.description.fundingTextShenzhen Science and Technology Fundingen_US
dc.description.pubStatusPublisheden_US
dc.identifier.OPUS14782852-
dc.description.oaCategoryGreen (AAM)en_US
Appears in Collections:Journal/Magazine Article
Files in This Item:
File Description SizeFormat 
Zhang_FABP4_Biomarker_Knee.pdfPre-Published version696.54 kBAdobe PDFView/Open
Open Access Information
Status open access
File Version Final Accepted Manuscript
Access
View full-text via PolyU eLinks SFX Query
Show simple item record

Page views

136
Last Week
1
Last month
Citations as of Apr 14, 2025

Downloads

294
Citations as of Apr 14, 2025

SCOPUSTM   
Citations

31
Citations as of May 8, 2025

WEB OF SCIENCETM
Citations

34
Last Week
0
Last month
Citations as of May 8, 2025

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.