Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/77231
DC Field | Value | Language |
---|---|---|
dc.contributor | Department of Rehabilitation Sciences | en_US |
dc.contributor | School of Nursing | en_US |
dc.creator | Wang, EW | en_US |
dc.creator | Pang, MY | en_US |
dc.creator | Siu, PM | en_US |
dc.creator | Lai, CK | en_US |
dc.creator | Woo, J | en_US |
dc.creator | Collins, AR | en_US |
dc.creator | Benzie, IFF | en_US |
dc.date.accessioned | 2018-07-30T08:27:02Z | - |
dc.date.available | 2018-07-30T08:27:02Z | - |
dc.identifier.issn | 0964-7058 | en_US |
dc.identifier.uri | http://hdl.handle.net/10397/77231 | - |
dc.language.iso | en | en_US |
dc.publisher | HEC Press | en_US |
dc.rights | Posted with permission of the publisher. | en_US |
dc.rights | The following publication Wang, E. W. L., Pang, M. Y. C., Siu, P. M. F., Lai, C. K. Y., Woo, J., Collins, A. R., & Benzie, I. F. (2018). Vitamin D status and cardiometabolic risk factors in young adults in Hong Kong: associations and implications. Asia Pacific journal of clinical nutrition, 27(1), 231-237 is available at https://dx.doi.org/10.6133/apjcn.022017.08 | en_US |
dc.title | Vitamin d status and cardiometabolic risk factors in young adults in Hong Kong : associations and implications | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.spage | 231 | en_US |
dc.identifier.epage | 237 | en_US |
dc.identifier.volume | 27 | en_US |
dc.identifier.issue | 1 | en_US |
dc.identifier.doi | 10.6133/apjcn.022017.08 | en_US |
dcterms.abstract | Background and Objectives: Vitamin D deficiency is reportedly common, but we lack data from young adults. Such data are of interest because epidemiological data support vitamin D as a possible risk modulator for diabetes and cardiovascular ('cardiometabolic') disease. Our objectives were to assess vitamin D status (as plasma 25(OH)D concentration) and investigate associations between this and biomarkers of cardiometabolic disease risk in a group of still-healthy young adults in Hong Kong. Methods and Study Design: In this observational study, fasting venous blood was collected from 196 (63 males, 133 females), young (18-26 years) non-smoking, nonobese, consenting adults in good general health. Plasma 25(OH)D was measured by LC-MS/MS. A panel of established cardiometabolic risk factors (HbA1c, plasma glucose, lipid profile, hsCRP) and blood pressure were also measured. Results: Mean (SD) plasma 25(OH)D concentration was 42.1 (13.0), with range 15.7-86.8 nmol/L; 141/196 subjects (72%) had vitamin D deficiency (25(OH)D < 50 nmol/L); 13/184 (6.6%) were severely deficient (< 25 nmol/L). Inverse association was seen between 25(OH)D and fasting glucose (r=-0.18; p < 0.05). Higher HbA1c and TC:HDL-C ratio and lower HDL-C were seen in those with plasma 25(OH)D < 25 nmol/L (p < 0.05). Conclusions: Vitamin D deficiency was highly prevalent and associated with poorer cardiometabolic risk profile in these young adults. Public health strategies for addressing vitamin D deficiency are needed urgently. These new data provide support for further study on vitamin D deficiency as a modifiable risk factor for cardiometabolic disease and the ameliorative effects of increased vitamin D intake on cardiometabolic disease risk profile of vitamin D-deficient young adults. | en_US |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Asia Pacific journal of clinical nutrition, 2018, v. 27, no. 1, p. 231-237 | en_US |
dcterms.isPartOf | Asia Pacific journal of clinical nutrition | en_US |
dcterms.issued | 2018 | - |
dc.identifier.scopus | 2-s2.0-85038877943 | - |
dc.identifier.eissn | 1440-6047 | en_US |
dc.identifier.rosgroupid | 2017000797 | - |
dc.description.ros | 2017-2018 > Academic research: refereed > Publication in refereed journal | en_US |
dc.description.validate | 201807 bcrc | en_US |
dc.description.oa | Version of Record | en_US |
dc.identifier.FolderNumber | a0761-n02 | - |
dc.identifier.SubFormID | 1445 | - |
dc.description.fundingSource | RGC | en_US |
dc.description.fundingText | PolyU 5601/13M | en_US |
dc.description.pubStatus | Published | en_US |
Appears in Collections: | Journal/Magazine Article |
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