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http://hdl.handle.net/10397/68223
Title: | On relationship of Z-curve and fourier approaches for DNA coding sequence classification | Authors: | Law, NF Cheng, KO Siu, WC |
Issue Date: | 2006 | Source: | Bioinformation, 2006, v. 1, no. 7, p. 242-246 | Abstract: | Z-curve features are one of the popular features used in exon/intron classification. We showed that although both Z-curve and Fourier approaches are based on detecting 3-periodicity in coding regions, there are significant differences in their spectral formulation. From the spectral formulation of the Z-curve, we obtained three modified sequences that characterize different biological properties. Spectral analysis on the modified sequences showed a much more prominent 3-periodicity peak in coding regions than the Fourier approach. For long sequences, prominent peaks at 2Π/3 are observed at coding regions, whereas for short sequences, clearly discernible peaks are still visible. Better classification can be obtained using spectral features derived from the modified sequences. | Keywords: | Z-Curve approach FT analysis DNA sequence Coding region Spectral analysis |
Publisher: | Biomedical Informatics Publishing Group | Journal: | Bioinformation | ISSN: | 0973-2063 | Rights: | © 2006 Biomedical Informatics Publishing Group This is an open-access article, which permits unrestricted use, distribution, and reproduction in any medium, for non-commercial purposes, provided the original author and source are credited. The following publication Law, N. F., Cheng, K. O., & Siu, W. C. (2006). On relationship of Z-curve and fourier approaches for DNA coding sequence classification. Bioinformation, 1(7), 242-246 is available at https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1891701/ |
Appears in Collections: | Journal/Magazine Article |
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