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Title: Parametric images in assessing bone grafts using dynamic ¹⁸F-fluoride PET
Authors: Wen, L
Eberl, S
Feng, DD
Stalley, P
Huang, G
Fulham, MJ
Issue Date: 2011
Source: International journal of molecular imaging, v. 2011, 189830, p.1-8
Abstract: The early identification of graft failure would improve patient management. ¹⁸F-fluoride is a suitable tracer for quantifying bone metabolism. Performance of parametric images constructed by Patlak graphical analysis (PGA) with various time periods was evaluated in the analysis of dynamic ¹⁸F-fluoride PET studies of eight patients with fibula bone grafts after limb salvage surgery. The PGA parametric image approach tended to underestimate influx rate. The linear portion of PGA analysis was found to be from 10 to 50 min. It shows promise in providing a quantitative assessment of the viability of bone grafts.
Publisher: Hindawi Publishing Corporation
Journal: International journal of molecular imaging 
ISSN: 2090-1712
EISSN: 2090-1720
DOI: 10.1155/2011/189830
Rights: Copyright © 2011 Lingfeng Wen et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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