Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/6603
| Title: | A Chan dietary intervention enhances executive functions and anterior cingulate activity in autism spectrum disorders : a randomized controlled trial | Authors: | Chan, AS Sze, SL Han, YMY Cheung, MC |
Issue Date: | 2012 | Source: | Evidence-based complementary and alternative medicine, 2012, v. 2012, 262136, p. 1-11 | Abstract: | Executive dysfunctions have been found to be related to repetitive/disinhibited behaviors and social deficits in autism spectrum disorders (ASDs). This study aims to investigate the potential effect of a Shaolin-medicine-based dietary modification on improving executive functions and behavioral symptoms of ASD and exploring the possible underlying neurophysiological mechanisms. Twenty-four children with ASD were randomly assigned into the experimental (receiving dietary modification for one month) and the control (no modification) groups. Each child was assessed on his/her executive functions, behavioral problems based on parental ratings, and event-related electroencephalography (EEG) activity during a response-monitoring task before and after the one month. The experimental group demonstrated significantly improved mental flexibility and inhibitory control after the diet modification, which continued to have a large effect size within the low-functioning subgroup. Such improvements coincided with positive evaluations by their parents on social communication abilities and flexible inhibitory control of daily behaviors and significantly enhanced event-related EEG activity at the rostral and subgenual anterior cingulate cortex. In contrast, the control group did not show any significant improvements. These positive outcomes of a one-month dietary modification on children with ASD have implicated its potential clinical applicability for patients with executive function deficits. | Keywords: | Electromagnetic tomography Response-inhibition Prefrontal cortex Central coherence Vegetarian diets Young-children Deficits Adults Brain Individuals |
Publisher: | Hindawi Publishing Corporation | Journal: | Evidence-based complementary and alternative medicine | ISSN: | 1741-427X | EISSN: | 1741-4288 | DOI: | 10.1155/2012/262136 | Rights: | Copyright © 2012 Agnes S. Chan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Appears in Collections: | Journal/Magazine Article |
Files in This Item:
| File | Description | Size | Format | |
|---|---|---|---|---|
| Chan_Dietary_Intervention_Autism.pdf | 1.7 MB | Adobe PDF | View/Open |
Access
View full-text via PolyU eLinks 
Page views
49
Last Week
1
1
Last month
Citations as of Jun 4, 2023
Downloads
54
Citations as of Jun 4, 2023
SCOPUSTM
Citations
14
Last Week
0
0
Last month
0
0
Citations as of Jun 1, 2023
WEB OF SCIENCETM
Citations
14
Last Week
0
0
Last month
0
0
Citations as of Jun 1, 2023
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.