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http://hdl.handle.net/10397/6586
| Title: | Non-invasive blood glucose measurement by near infrared spectroscopy : machine drift, time drift and physiological effect | Authors: | Lam, SCH Chung, J Fan, KL Wong, TKS |
Issue Date: | 2010 | Source: | Spectroscopy, 2010, v. 24, no. 6, p. 629-639 | Abstract: | The aim of this paper is to evaluate development of the non-invasive blood glucose measurement of near infrared (NIR) spectroscopy. The results showed that NIR spectroscopy might obtain glucose concentration of up to 200% difference under a same environmental condition with two months apart due to time and machine drifts. These effects can restrict the development of the non-invasive blood glucose measurement. Partial least square (PLS) regression was used, which showed advantage over using simple absorbance for glucose concentration. Non-invasive blood glucose measurement of health subjects (non-diabetics) was also investigated. The results showed that R correlation coefficient of prediction (Rp) was 0.48 and root mean square of prediction (rmsep) was 1.34 mmol/l. The error was mainly due to the physiological effect of different subjects. | Keywords: | Spectroscopy Machine drift Time drift Physiological effect PLS PDS Beer's law |
Publisher: | Hindawi Publishing Corporation | Journal: | Spectroscopy | ISSN: | 0712-4813 (print) 1875-922X (online) |
DOI: | 10.3233/SPE-2010-0485 | Rights: | Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| Appears in Collections: | Journal/Magazine Article |
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|---|---|---|---|---|
| Lam_Blood_Glucose_Spectroscopy.pdf | 558.1 kB | Adobe PDF | View/Open |
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