Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/65437
DC Field | Value | Language |
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dc.contributor | Institute of Textiles and Clothing | - |
dc.creator | He, L | - |
dc.creator | Li, S | - |
dc.creator | Chung, CTW | - |
dc.creator | Gao, C | - |
dc.creator | Xin, JH | - |
dc.date.accessioned | 2017-05-22T02:08:36Z | - |
dc.date.available | 2017-05-22T02:08:36Z | - |
dc.identifier.uri | http://hdl.handle.net/10397/65437 | - |
dc.language.iso | en | en_US |
dc.publisher | Nature Publishing Group | en_US |
dc.rights | This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ | en_US |
dc.rights | © The Author(s) 2016 | en_US |
dc.rights | The following publication He, L. et al. Constructing safe and durable antibacterial textile surfaces using a robust graft-to strategy via covalent bond formation. Sci. Rep. 6, 36327 (2016) is available at https://dx.doi.org/10.1038/srep36327 | en_US |
dc.title | Constructing safe and durable antibacterial textile surfaces using a robust graft-to strategy via covalent bond formation | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.volume | 6 | - |
dc.identifier.doi | 10.1038/srep36327 | - |
dcterms.abstract | Recently zwitterionic materials have been widely applied in the biomedical and bioengineering fields due to their excellent biocompatibility. Inspired by these, this study presents a graft-to strategy via covalent bond formation to fabricate safe and durable antibacterial textile surfaces. A novel zwitterionic sulfobetaine containing triazine reactive group was specifically designed and synthesized. MTT assay showed that it had no obvious cytotoxicity to human skin HaCaT cells as verified by ca. 89.9% relative viability at a rather high concentration of 0.8 mg·mL-1. In the evaluation for its skin sensitization, the maximum score for symptoms of erythema and edema in all tests were 0 in all observation periods. The sulfobetaine had a hydrophilic nature and the hydrophilicity of the textiles was enhanced by 43.9% when it was covalently grafted onto the textiles. Moreover, the textiles grafted with the reactive sulfobetaine exhibited durable antibacterial activities, which was verified by the fact that they showed antibacterial rates of 97.4% against gram-positive S. aureus and 93.2% against gram-negative E. coli even after they were laundered for 30 times. Therefore, the titled zwitterionic sulfobetaine is safe to human for healthcare and wound dressing and shows a promising prospect on antibacterial textile application. | - |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Scientific reports, 3 2016, v. 6, no. , 36327, p. 1-9 | - |
dcterms.isPartOf | Scientific reports | - |
dcterms.issued | 2016 | - |
dc.identifier.isi | WOS:000386981100001 | - |
dc.identifier.scopus | 2-s2.0-84994626515 | - |
dc.identifier.ros | 2016004504 | - |
dc.identifier.eissn | 2045-2322 | - |
dc.identifier.artn | 36327 | - |
dc.identifier.rosgroupid | 2016004420 | - |
dc.description.ros | 2016-2017 > Academic research: refereed > Publication in refereed journal | - |
dc.description.validate | 201804_a bcma | - |
dc.description.oa | Version of Record | en_US |
dc.identifier.FolderNumber | OA_IR/PIRA | en_US |
dc.description.pubStatus | Published | en_US |
dc.description.oaCategory | CC | en_US |
Appears in Collections: | Journal/Magazine Article |
Files in This Item:
File | Description | Size | Format | |
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He_Constructing_Safe_Antibacterial.pdf | 2.3 MB | Adobe PDF | View/Open |
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