Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/2303
DC Field | Value | Language |
---|---|---|
dc.contributor | Institute of Textiles and Clothing | - |
dc.contributor | Department of Health Technology and Informatics | - |
dc.creator | Li, J | - |
dc.creator | Chen, Y | - |
dc.creator | Mak, AFT | - |
dc.creator | Tuan, RS | - |
dc.creator | Li, L | - |
dc.creator | Li, Y | - |
dc.date.accessioned | 2014-12-11T08:22:55Z | - |
dc.date.available | 2014-12-11T08:22:55Z | - |
dc.identifier.issn | 1742-7061 | - |
dc.identifier.uri | http://hdl.handle.net/10397/2303 | - |
dc.language.iso | en | en_US |
dc.publisher | Elsevier Ltd. | en_US |
dc.rights | Acta Biomaterialia © 2010 Elsevier Ltd. The journal web site is located at http://www.sciencedirect.com. | en_US |
dc.subject | Ice-based microporogens | en_US |
dc.subject | Scaffold | en_US |
dc.subject | Collagen | en_US |
dc.subject | Hydroxyapatite | en_US |
dc.subject | Poly(L-lactic acid) | en_US |
dc.title | A one-step method to fabricate PLLA scaffolds with deposition of bioactive hydroxyapatite and collagen using ice-based microporogens | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.spage | 2013 | - |
dc.identifier.epage | 2019 | - |
dc.identifier.volume | 6 | - |
dc.identifier.issue | 6 | - |
dc.identifier.doi | 10.1016/j.actbio.2009.12.008 | - |
dcterms.abstract | Porous poly(L-lactic acid) (PLLA) scaffolds with bioactive coatings were prepared by a novel one-step method. In this process, ice-based microporogens containing bioactive molecules, such as hydroxyapatite (HA) and collagen, served as both porogens to form the porous structure and vehicles to transfer the bioactive molecules to the inside of PLLA scaffolds in a single step. Based on scanning electron microscopy, energy-dispersive X-ray spectroscopy, X-ray diffraction and Fourier transform infrared spectroscopy analysis, the bioactive components were found to be transferred successfully from the porogens to PLLA scaffolds evenly. Osteoblast cells were used to evaluate the cellular behaviors of the composite scaffolds. After culturing for 8 days, MTT assay and alkaline phosphatase activity results suggested that HA/collagen could improve the interactions between osteoblast cells and the polymeric scaffold. | - |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Acta Biomaterialia, June 2010, v. 6, no. 6, p. 2013-2019 | - |
dcterms.isPartOf | Acta Biomaterialia | - |
dcterms.issued | 2010-06 | - |
dc.identifier.isi | WOS:000278250100014 | - |
dc.identifier.scopus | 2-s2.0-77956622277 | - |
dc.identifier.pmid | 20004261 | - |
dc.identifier.rosgroupid | r46087 | - |
dc.description.ros | 2009-2010 > Academic research: refereed > Publication in refereed journal | - |
dc.description.oa | Accepted Manuscript | en_US |
dc.identifier.FolderNumber | OA_IR/PIRA | en_US |
dc.description.pubStatus | Published | en_US |
dc.description.oaCategory | Green (AAM) | en_US |
Appears in Collections: | Journal/Magazine Article |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
ACTBIO.pdf | Pre-published version | 7.13 MB | Adobe PDF | View/Open |
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