Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/1885
PIRA download icon_1.1View/Download Full Text
Title: Dynamic imaging and tracer kinetic modeling for emission tomography using rotating detectors
Authors: Lau, CH
Feng, DD
Hutton, BF
Lun, PKD 
Siu, WC 
Issue Date: Dec-1998
Source: IEEE transactions on medical imaging, Dec. 1998, v. 17, no. 6, p. 986-994
Abstract: When performing dynamic studies using emission tomography the tracer distribution changes during acquisition of a single set of projections. This is particularly true for some positron emission tomography (PET) systems which, like single photon emission computed tomography (SPECT), acquire data over a limited angle at any time, with full projections obtained by rotation of the detectors. In this paper, an approach is proposed for processing data from these systems, applicable to either PET or SPECT.
A method of interpolation, based on overlapped parabolas, is used to obtain an estimate of the total counts in each pixel of the projections for each required frame-interval, which is the total time to acquire a single complete set of projections necessary for reconstruction. The resultant projections are reconstructed using traditional filtered backprojection (FBP) and tracer kinetic parameters are estimated using a method which relies on counts integrated over the frame-interval rather than instantaneous values. Simulated data were used to illustrate the technique’s capabilities with noise levels typical of those encountered in either PET or SPECT. Dynamic datasets were constructed, based on kinetic parameters for fluoro-deoxy-glucose (FDG) and use of either a full ring detector or rotating detector acquisition. For the rotating detector, use of the interpolation scheme provided reconstructed dynamic images with reduced artefacts compared to unprocessed data or use of linear interpolation. Estimates for the metabolic rate of glucose had similar bias to those obtained from a full ring detector.
Keywords: Coincidence detection
Emission tomography
PET
SPECT
Tracer kinetic modeling
Publisher: Institute of Electrical and Electronics Engineers
Journal: IEEE transactions on medical imaging 
ISSN: 0278-0062 (print)
1558-254X (online)
DOI: 10.1109/42.746631
Rights: © 1998 IEEE. Personal use of this material is permitted. However, permission to reprint/republish this material for advertising or promotional purposes or for creating new collective works for resale or redistribution to servers or lists, or to reuse any copyrighted component of this work in other works must be obtained from the IEEE.
This material is presented to ensure timely dissemination of scholarly and technical work. Copyright and all rights therein are retained by authors or by other copyright holders. All persons copying this information are expected to adhere to the terms and constraints invoked by each author's copyright. In most cases, these works may not be reposted without the explicit permission of the copyright holder.
Appears in Collections:Journal/Magazine Article

Files in This Item:
File Description SizeFormat 
Lau_et_al_Emission_Tomography_Rotating.pdf551.86 kBAdobe PDFView/Open
Open Access Information
Status open access
File Version Version of Record
Access
View full-text via PolyU eLinks SFX Query
Show full item record

Page views

113
Last Week
2
Last month
Citations as of Mar 24, 2024

Downloads

92
Citations as of Mar 24, 2024

SCOPUSTM   
Citations

6
Last Week
0
Last month
0
Citations as of Mar 28, 2024

WEB OF SCIENCETM
Citations

5
Last Week
0
Last month
0
Citations as of Mar 28, 2024

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.