Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/119855
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Title: SearchRAG : can search engines be helpful for LLM-based medical question answering?
Authors: Shi, Y
Yang, T
Chen, C
Li, Q
Liu, T
Li, X
Liu, N 
Issue Date: 2025
Source: 2025 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Wuhan, China, December 15-18 2025, p. 4051-4056
Abstract: Large Language Models (LLMs) have shown remarkable capabilities in general domains but often struggle with tasks requiring specialized knowledge. Conventional Retrieval-Augmented Generation (RAG) techniques typically retrieve external information from static knowledge bases, which can be outdated or incomplete, missing fine-grained clinical details essential for accurate medical question answering. In this work, we propose SearchRAG, a novel framework that overcomes these limitations by leveraging real-time search engines. Our method employs synthetic query generation to convert complex medical questions into search-engine-friendly queries and utilizes uncertainty-based knowledge selection to filter and incorporate the most relevant and informative medical knowledge into the LLM's input. Experimental results demonstrate that our method significantly improves response accuracy in medical question answering tasks, particularly for complex questions requiring detailed and up-to-date knowledge. We provide our code here11https://github.com/sycny/SearchRAG.
Keywords: LLMs
Medical QA
RAG
Search engine
Publisher: Institute of Electrical and Electronics Engineers
ISBN: 979-8-3315-1557-7 (Electronic)
979-8-3315-1558-4 (Print on Demand(PoD))
DOI: 10.1109/BIBM66473.2025.11356025
Description: 2025 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Wuhan, China, December 15-18 2025
Rights: © 2025 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other uses, in any current or future media, including reprinting/republishing this material for advertising or promotional purposes, creating new collective works, for resale or redistribution to servers or lists, or reuse of any copyrighted component of this work in other works.
The following publication Y. Shi et al., "SearchRAG: Can Search Engines Be Helpful for LLM-Based Medical Question Answering?," 2025 IEEE International Conference on Bioinformatics and Biomedicine (BIBM), Wuhan, China, 2025, pp. 4051-4056 is available at https://doi.org/10.1109/BIBM66473.2025.11356025.
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