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http://hdl.handle.net/10397/119630
| Title: | A highly selective quinolizinium-based fluorescent probe for cysteine detection | Authors: | O, WY Chan, WC Xu, C Deng, JR Ko, BCB Wong, MK |
Issue Date: | 2021 | Source: | RSC advances, 2021, v. 11, no. 53, p. 33294-33299 | Abstract: | A novel fluorescent quinolizinium-based turn-off probe has been developed for selective detection of cysteine. The probe showed high selectivity and sensitivity towards cysteine over other amino acids including the similarly structured homocysteine and glutathione with a detection limit of 0.18 μM (S/N = 3). It was successfully applied to cysteine detection in living cells with low cytotoxicity and quantitative analysis of spiked mouse serum samples with moderate to good recovery (96-109%). | Publisher: | Royal Society of Chemistry | Journal: | RSC advances | EISSN: | 2046-2069 | DOI: | 10.1039/d1ra06104f | Rights: | © 2021 The Author(s). Published by the Royal Society of Chemistry. This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence (http://creativecommons.org/licenses/by-nc/3.0/). The following publication Wa-Yi, O., Chan, W. C., Xu, C., Deng, J. R., Ko, B. C. B., & Wong, M. K. (2021). A highly selective quinolizinium-based fluorescent probe for cysteine detection. RSC advances, 11(53), 33294-33299 is available at https://doi.org/10.1039/D1RA06104F. |
| Appears in Collections: | Journal/Magazine Article |
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