Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/116728
PIRA download icon_1.1View/Download Full Text
DC FieldValueLanguage
dc.contributorSchool of Optometry-
dc.contributorResearch Centre for SHARP Vision-
dc.creatorWu, Yen_US
dc.creatorChen, Xen_US
dc.creatorZhang, Wen_US
dc.creatorLiu, Sen_US
dc.creatorSum, WMRen_US
dc.creatorWu, Xen_US
dc.creatorShang, Xen_US
dc.creatorKee, CSen_US
dc.creatorHe, Men_US
dc.creatorShi, Den_US
dc.date.accessioned2026-01-15T08:03:51Z-
dc.date.available2026-01-15T08:03:51Z-
dc.identifier.urihttp://hdl.handle.net/10397/116728-
dc.language.isoenen_US
dc.publisherCell Pressen_US
dc.rights© 2025 The Author(s). Published by Elsevier Inc.en_US
dc.rightsThis is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).en_US
dc.rightsThe following publicationen_US
dc.titleChatMyopia : an AI agent for myopia-related consultation in primary eye care settingsen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.volume28en_US
dc.identifier.issue11en_US
dc.identifier.doi10.1016/j.isci.2025.113768en_US
dcterms.abstractLarge language models (LLMs) show promise for tailored healthcare communication but face challenges in interpretability and multi-task integration, particularly for domain-specific needs such as myopia, and their real-world effectiveness as patient education tools has yet to be demonstrated. Here, we introduce ChatMyopia, an LLM-based AI agent to address text- and image-based inquiries related to myopia. ChatMyopia integrates an image classification tool and a retrieval-augmented knowledge base built from literature, expert consensus, and clinical guidelines. Myopic maculopathy grading task, single question examination, and human evaluations validated its ability to deliver accurate and safe responses with high scalability and interpretability. In a randomized controlled trial, it significantly improved patient satisfaction compared to traditional leaflets, enhancing patient education in accuracy, empathy, disease awareness, and communication with eye care practitioners. These findings highlight ChatMyopia’s potential as a valuable supplement to enhance patient education and improve satisfaction with medical services in primary eye care settings.-
dcterms.abstractGraphical abstract: [Figure not available: see fulltext.]-
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationiScience, 21 Nov. 2025, v. 28, no. 11, 113768en_US
dcterms.isPartOfiScienceen_US
dcterms.issued2025-11-21-
dc.identifier.eissn2589-0042en_US
dc.description.validate202601 bcch-
dc.description.oaVersion of Recorden_US
dc.identifier.FolderNumbera4266a-
dc.identifier.SubFormID52490-
dc.description.fundingSourceOthersen_US
dc.description.fundingTextThe study was supported by the Start-up Fund for RAPs under the Strategic Hiring Scheme (P0048623) from the Hong Kong Polytechnic University, the Global STEM Professorship Scheme (P0046113) from HKSAR, and the Henry G. Leong Endowed Professorship in Elderly Vision Health. We thank the InnoHK HKSAR Government for providing valuable support. The research work described in this article was conducted in the JC STEM Lab of Innovative Light Therapy for Eye Diseases, funded by The Hong Kong Jockey Club Charities Trust.en_US
dc.description.pubStatusPublisheden_US
dc.description.oaCategoryCCen_US
Appears in Collections:Journal/Magazine Article
Files in This Item:
File Description SizeFormat 
1-s2.0-S2589004225020292-main.pdf6.73 MBAdobe PDFView/Open
Open Access Information
Status open access
File Version Version of Record
Access
View full-text via PolyU eLinks SFX Query
Show simple item record

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.