Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/115681
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Title: The role of intolerance of uncertainty in explaining mental health symptoms among adults in Hong Kong
Authors: Cao, Y 
Kwan, GSY
Siu, JYM 
Schmidt, NB
Shum, DHK 
Issue Date: Nov-2025
Source: Journal of psychiatric research, Nov. 2025, v. 191, p. 372-381
Abstract: Intolerance of uncertainty (IU) has been reported as a transdiagnostic risk factor for a variety of mental health outcomes, including post-traumatic stress disorder (PTSD) in response to an acute stressor. However, there is relatively little understanding of the impact of a population-wide long-term stressor (e.g., a pandemic) and its associated risk factors on mental health. The current study evaluated the association between IU components, post-traumatic stress symptoms, general anxiety, and depression in the context of a long-term stressor (towards the end of the COVID-19 pandemic). From October 27, 2022 to December 23, 2022, cross-sectional data were collected through a telephone survey from a sample of 3023 adults aged 18–96 (M = 57.08, SD = 19.05) who lived in Hong Kong. The results indicated that 8.8 % of the respondents were likely to have PTSD (based on the IES-R), 10.4 % depression (based on the PHQ-2), and 10 % general anxiety (based on the GAD-2). IU components were significant risk factors for experiencing more severe PTSD symptoms and general psychological distress in terms of general anxiety and depression. The results of this study highlight the important and differential roles of IU components in explaining psychological trauma and poor mental health in response to a long-term stressor.
Keywords: Anxiety
COVID-19
Depression
Intolerance of uncertainty
Posttraumatic stress disorder
Publisher: Elsevier Ltd
Journal: Journal of psychiatric research 
ISSN: 0022-3956
EISSN: 1879-1379
DOI: 10.1016/j.jpsychires.2025.09.073
Rights: © 2025 The Authors. Published by Elsevier Ltd. This is an open access article under the CC BY-NC license (http://creativecommons.org/licenses/by- nc/4.0/).
The following publication Cao, Y., Kwan, G. S. Y., Siu, J. Y.-m., Schmidt, N. B., & Shum, D. H. K. (2025). The role of intolerance of uncertainty in explaining mental health symptoms among adults in Hong Kong. Journal of Psychiatric Research, 191, 372–381 is available at https://doi.org/10.1016/j.jpsychires.2025.09.073.
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