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Title: Economic evaluation of an enhanced post-discharge home-based care program for stroke survivors
Authors: Wong, AKC 
Wang, SL 
So, C 
Lian, J 
Yan, Y
Li, H
Wu, L
Pei, H
Wang, W
Wong, FKY 
Issue Date: Apr-2024
Source: Value in health, Apr. 2024, v. 27, no. 4, p. 405-414
Abstract: Objectives: To examine the cost-effectiveness of an enhanced postdischarge home-based care program for stroke survivors compared with usual care.
Methods: This was a trial-based economic evaluation study. One hundred and sixteen patients with ischemic stroke were recruited from neurology units in a Chinese hospital and randomized into intervention (n = 58) or usual care groups (n = 58). The intervention commenced with predischarge planning and transitioned to home follow-up postdischarge. Trained nurse case managers supported by an interdisciplinary team provided comprehensive assessment, individualized goal setting, and skill training to support home-based rehabilitation for intervention group participants. Standard care was provided to usual care group participants. Total cost and quality-adjusted life-years gained at 3-month (T1), 6-month (T2), and 12-month (T3) follow-ups were calculated. The incremental cost-effectiveness ratios between the groups were obtained.
Results: The intervention group showed a significant increase in utility compared with the usual care group at T1 (P = .003), T2 (P = .007), and T3 (P < .001). The average total QALY gain from baseline for the intervention group was higher than for the usual care group at all time points. The likelihood of being cost-effective ranged from 61.9% to 67.2% from the provider perspective, and from 59.7% to 66.8% from the societal perspective.
Conclusions: The results showed that the intervention program was cost-effective with significantly higher quality-adjusted life-years for stroke survivors when compared with usual care. It provides economic evidence to support the development of home-based stroke rehabilitation program, especially in the low- and middle-income countries.
Keywords: Economics
Standard of care
Stroke
Stroke rehabilitation
Publisher: Elsevier Inc.
Journal: Value in health 
ISSN: 1098-3015
EISSN: 1524-4733
DOI: 10.1016/j.jval.2024.01.012
Rights: Copyright © 2024, International Society for Pharmacoeconomics and Outcomes Research, Inc. Published by Elsevier Inc.
© 2024. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
The following publication Wong, A. K. C., Wang, S. L., So, C., Lian, J., Yan, Y., Li, H., Wu, L., Pei, H., Wang, W., & Wong, F. K. Y. (2024). Economic Evaluation of an Enhanced Post-Discharge Home-Based Care Program for Stroke Survivors. Value in Health, 27(4), 405-414 is available at https://doi.org/10.1016/j.jval.2024.01.012.
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