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Title: Trajectories of instrumental activities of daily living and their predictors among older men and women in Hong Kong : a 14-year prospective study
Authors: Lu, Z
Leung, J
Auyeung, TW
Lee, J
Lo, K 
Lai, KS
Lam, K
Woo, J
Kwok, T
Issue Date: Feb-2025
Source: Gerontology : international journal of experimental, clinical, behavioral, regenerative and technical gerontology, Feb. 2025, v. 71, no. 2, p. 81-87
Abstract: Introduction: This study aimed to identify the different patterns of trajectories in instrumental activities of daily living (IADL) in older men and women, respectively, and to examine the factors associated with the different trajectories.
Methods: We included 2,088 participants with an average age of 70.8 years at baseline from the MrOS and MsOS Hong Kong cohort study (men: 1,074; women: 1,014) and followed up the participants for over 14 years. The group-based trajectory models were used to identify IADL trajectories. Binary logistic regression and multinominal logistic regression models were used to identify factors associated with different trajectories.
Results: Two distinct trajectories were identified for men including “slow decliners” (92.6% of men) and “rapid decliners” (7.4%), while three distinct trajectories were identified for women including “slow decliners” (43.5% of women), “intermediate decliners” (48.2%), and “rapid decliners” (8.3%). Being overweight or obese and slow walking speed were common predictors of more rapid IADL declining trajectories in both men and women. Particularly, having stroke, weak grip strength, and higher level of PM2.5 were associated with the higher risk of being rapid decliners in men, and having osteoporosis and poor self-rated health were associated with more rapid IADL declining trajectories in women.
Conclusion: Sex differences were observed in the IADL declining trajectories. Several risk factors were found that could possibly be useful in identifying and preventing functional impairments in an earlier stage.
Keywords: Group-based modeling
Instrumental activities of daily living impairment
Older people
Trajectories
Publisher: S. Karger AG
Journal: Gerontology : international journal of experimental, clinical, behavioral, regenerative and technical gerontology 
ISSN: 0304-324X
EISSN: 1423-0003
DOI: 10.1159/000543378
Rights: ©2025 The Author(s). Published by S. Karger AG, Basel
This article is licensed under the Creative Commons AttributionNonCommercial 4.0 International License (CCBY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
The following publication Lu, Z., Leung, J., Auyeung, T., Lee, J., Lo, K., Lai, K.-S., Lam, K., Woo, J., & Kwok, T. (2025). Trajectories of Instrumental Activities of Daily Living and Their Predictors among Older Men and Women in Hong Kong: A 14-Year Prospective Study. Gerontology, 71(2), 81-87 is available at https://doi.org/10.1159/000543378.
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