Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/107488
DC Field | Value | Language |
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dc.contributor | School of Optometry | - |
dc.creator | Jiang, F | - |
dc.creator | Wang, D | - |
dc.creator | Xiao, O | - |
dc.creator | Guo, X | - |
dc.creator | Yin, Q | - |
dc.creator | Luo, L | - |
dc.creator | He, M | - |
dc.creator | Li, Z | - |
dc.date.accessioned | 2024-06-27T01:33:47Z | - |
dc.date.available | 2024-06-27T01:33:47Z | - |
dc.identifier.issn | 2168-6165 | - |
dc.identifier.uri | http://hdl.handle.net/10397/107488 | - |
dc.language.iso | en | en_US |
dc.publisher | American Medical Association | en_US |
dc.rights | © 2024 American Medical Association. All rights reserved. | en_US |
dc.rights | The following publication Yuan Y, Xiong R, Wang W, et al. Long-Term Risk and Prediction of Progression in Primary Angle Closure Suspect. JAMA Ophthalmol. 2024;142(3):216–223 is available at https://dx.doi.org/10.1001/jamaophthalmol.2023.5286. | en_US |
dc.title | Four-year progression of myopic maculopathy in children and adolescents with high myopia | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.spage | 180 | - |
dc.identifier.epage | 186 | - |
dc.identifier.volume | 142 | - |
dc.identifier.issue | 3 | - |
dc.identifier.doi | 10.1001/jamaophthalmol.2023.6319 | - |
dcterms.abstract | Importance : Individuals with high myopia younger than 18 years are at relatively high risk of progressively worsening myopic maculopathy. Additional studies are needed to investigate the progression of myopic maculopathy in this age group, as well as the risk factors associated with progression. | - |
dcterms.abstract | Objective : To investigate the 4-year progression of myopic maculopathy in children and adolescents with high myopia, and to explore potential risk factors. | - |
dcterms.abstract | Design, Setting, and Participants : This hospital-based observational study with 4-year follow-up included a total of 548 high myopic eyes (spherical power −6.00 or less diopters) of 274 participants aged 7 to 17 years. Participants underwent comprehensive ophthalmic examination at baseline and 4-year follow-up. Myopic maculopathy was accessed by the International Photographic Classification and Grading System. The data analysis was performed from August 1 to 15, 2023. | - |
dcterms.abstract | Main Outcomes and Measures : The progression of myopic maculopathy progression over 4 years and associated risk factors. | - |
dcterms.abstract | Results : The 4-year progression of myopic maculopathy was found in 67 of 548 eyes (12.2%) of 274 participants (138 girls [50.4%] at baseline and 4-year follow-up) with 88 lesion changes, including new signs of the tessellated fundus in 16 eyes (18.2%), diffuse atrophy in 12 eyes (13.6%), patchy atrophy in 2 eyes (2.3%), lacquer cracks in 9 eyes (10.2%), and enlargement of diffuse atrophy in 49 eyes (55.7%). By multivariable analysis, worse best-corrected visual acuity (odds ratio [OR], 6.68; 95% CI, 1.15-38.99; P = .04), longer axial length (AL) (OR, 1.73; 95% CI, 1.34-2.24; P < .001), faster AL elongation (OR, 302.83; 95% CI, 28.61-3205.64; P < .001), and more severe myopic maculopathy (diffuse atrophy; OR, 4.52; 95% CI, 1.98-10.30; P < .001 and patchy atrophy; OR, 3.82; 95% CI, 1.66-8.80; P = .002) were associated with myopic maculopathy progression. | - |
dcterms.abstract | Conclusions and Relevance : In this observational study, the progression of myopic maculopathy was observed in approximately 12% of pediatric high myopes for 4 years. The major type of progression was the enlargement of diffuse atrophy. Risk factors for myopic maculopathy progression were worse best-corrected visual acuity, longer AL, faster AL elongation, and more severe myopic maculopathy. These findings support consideration of follow-up in these individuals and trying to identify those at higher risk for progression. | - |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | JAMA ophthalmology, Mar. 2024, v. 142, no. 3, p. 180-186 | - |
dcterms.isPartOf | JAMA ophthalmology | - |
dcterms.issued | 2024-03 | - |
dc.identifier.scopus | 2-s2.0-85183926515 | - |
dc.identifier.eissn | 2168-6173 | - |
dc.description.validate | 202406 bcch | - |
dc.description.oa | Accepted Manuscript | en_US |
dc.identifier.FolderNumber | a2894 | en_US |
dc.identifier.SubFormID | 48664 | en_US |
dc.description.fundingSource | Others | en_US |
dc.description.fundingText | National Natural Science Foundation of China; Science and Technology Projects in Guangzhou; Fundamental Research Funds of the State Key Laboratory of Ophthalmology; Global STEM Professorship Scheme; Science and Technology Planning Project of Guangdong Province; Brien Holden Vision Institute in Australia | en_US |
dc.description.pubStatus | Published | en_US |
dc.date.embargo | en_US | |
dc.description.oaCategory | Green (AAM) | en_US |
Appears in Collections: | Journal/Magazine Article |
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File | Description | Size | Format | |
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Jiang_Four-year_Progression_Myopic.pdf | Pre-Published version | 946.67 kB | Adobe PDF | View/Open |
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