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http://hdl.handle.net/10397/107449
DC Field | Value | Language |
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dc.contributor | School of Optometry | - |
dc.creator | Yii, FSL | en_US |
dc.creator | He, M | en_US |
dc.creator | Chappell, F | en_US |
dc.creator | Bernabeu, MO | en_US |
dc.creator | MacGillivray, T | en_US |
dc.creator | Dhillon, B | en_US |
dc.creator | Tatham, A | en_US |
dc.creator | Strang, N | en_US |
dc.date.accessioned | 2024-06-24T07:02:48Z | - |
dc.date.available | 2024-06-24T07:02:48Z | - |
dc.identifier.issn | 0950-222X | en_US |
dc.identifier.uri | http://hdl.handle.net/10397/107449 | - |
dc.language.iso | en | en_US |
dc.publisher | Nature Publishing Group | en_US |
dc.rights | © The Author(s) 2023 | en_US |
dc.rights | This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. | en_US |
dc.rights | The following publication Yii, F.S., He, M., Chappell, F. et al. Higher intraocular pressure is associated with slower axial growth in children with non-pathological high myopia. Eye 38, 1208–1214 (2024) is available at https://doi.org/10.1038/s41433-023-02872-7. | en_US |
dc.title | Higher intraocular pressure is associated with slower axial growth in children with non-pathological high myopia | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.spage | 1208 | en_US |
dc.identifier.epage | 1214 | en_US |
dc.identifier.volume | 38 | en_US |
dc.identifier.issue | 6 | en_US |
dc.identifier.doi | 10.1038/s41433-023-02872-7 | en_US |
dcterms.abstract | Objectives: To investigate the association between intraocular pressure (IOP) and axial elongation rate in highly myopic children from the ZOC-BHVI High Myopia Cohort Study. | - |
dcterms.abstract | Methods: 162 eyes of 81 healthy children (baseline spherical equivalent: −6.25 D to −15.50 D) aged 7–12 years with non-pathological high myopia were studied over five biennial visits. The mean (SD) follow-up duration was 5.2 (3.3) years. A linear mixed-effects model (LMM) was used to assess the association between IOP (at time point t−1) and axial elongation rate (annual rate of change in AL from t−1 to t), controlling for a pre-defined set of covariates including sex, age, central corneal thickness, anterior chamber depth and lens thickness (at t−1). LMM was also used to assess the contemporaneous association between IOP and axial length (AL) at t, controlling for the same set of covariates (at t) as before. | - |
dcterms.abstract | Results: Higher IOP was associated with slower axial growth (β = −0.01, 95% CI −0.02 to −0.005, p = 0.001). There was a positive contemporaneous association between IOP and AL (β = 0.03, 95% CI 0.01–0.05, p = 0.004), but this association became progressively less positive with increasing age, as indicated by a negative interaction effect between IOP and age on AL (β = −0.01, 95% CI −0.01 to −0.003, p = 0.001). | - |
dcterms.abstract | Conclusions: Higher IOP is associated with slower rather than faster axial growth in children with non-pathological high myopia, an association plausibly confounded by the increased influence of ocular compliance on IOP. | - |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Eye, Apr. 2024, v. 38, no. 6, p. 1208-1214 | en_US |
dcterms.isPartOf | Eye | en_US |
dcterms.issued | 2024-04 | - |
dc.identifier.scopus | 2-s2.0-85179311150 | - |
dc.identifier.eissn | 1476-5454 | en_US |
dc.description.validate | 202406 bcch | - |
dc.description.oa | Version of Record | en_US |
dc.identifier.FolderNumber | a2869a | - |
dc.identifier.SubFormID | 48603 | - |
dc.description.fundingSource | Others | en_US |
dc.description.fundingText | Medical Research Council | en_US |
dc.description.pubStatus | Published | en_US |
dc.description.oaCategory | CC | en_US |
Appears in Collections: | Journal/Magazine Article |
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File | Description | Size | Format | |
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s41433-023-02872-7.pdf | 1.03 MB | Adobe PDF | View/Open |
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