Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/107308
Title: | Nanozymes for treating ocular diseases | Authors: | Wong, KY Wong, MS Liu, J |
Issue Date: | 2024 | Source: | Advanced healthcare materials, First published: 13 May 2024, Early View, https://doi.org/10.1002/adhm.202401309 | Abstract: | Nanozymes, characterized by their nanoscale size and enzyme-like catalytic activities, exhibit diverse therapeutic potentials, including anti-oxidative, anti-inflammatory, anti-microbial, and anti-angiogenic effects. These properties make them highly valuable in nanomedicine, particularly ocular therapy, bypassing the need for systemic delivery. Nanozymes show significant promise in tackling multi-factored ocular diseases, particularly those influenced by oxidation and inflammation, like dry eye disease, and age-related macular degeneration. Their small size, coupled with their ease of modification and integration into soft materials, facilitates the effective penetration of ocular barriers, thereby enabling targeted or prolonged therapy within the eye. This review is dedicated to exploring ocular diseases that are intricately linked to oxidation and inflammation, shedding light on the role of nanozymes in managing these conditions. Additionally, recent studies elucidating advanced applications of nanozymes in ocular therapeutics, along with their integration with soft materials for disease management, are discussed. Finally, this review outlines directions for future investigations aimed at bridging the gap between nanozyme research and clinical applications. | Keywords: | Eyes Inflammation Nanozymes Ocular diseases Oxidation |
Publisher: | Wiley-VCH Verlag GmbH & Co. KGaA | Journal: | Advanced healthcare materials | ISSN: | 2192-2640 | EISSN: | 2192-2659 | DOI: | 10.1002/adhm.202401309 | Rights: | © 2024 The Authors. Advanced Healthcare Materials published by Wiley-VCH GmbH. This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permitsuse, distribution and reproduction in any medium, provided the originalwork is properly cited and is not used for commercial purposes. The following publication K.-Y. Wong, M.-S. Wong, J. Liu, Nanozymes for Treating Ocular Diseases. Adv. Healthcare Mater. 2024, 2401309 is available at https://doi.org/10.1002/adhm.202401309. |
Appears in Collections: | Journal/Magazine Article |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
Wong_Nanozymes_Treating_Ocular.pdf | 5.34 MB | Adobe PDF | View/Open |
Page views
9
Citations as of Jun 30, 2024
Downloads
2
Citations as of Jun 30, 2024
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.