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Title: | Paranasal sinus angiosarcoma with facial paralysis as a novel manifestation : a case report and literature review | Authors: | Chai, CC Feng, XC Li, K Yan, ZX Tan, SY Weng, J Huang, F Huang, JP Zhu, XR Zhuo, XH Chen, H |
Issue Date: | 2023 | Source: | BMC Neurology, 2023, v. 23, 428 | Abstract: | Background Paranasal sinus angiosarcoma is an uncommon malignancy, with only a few reported cases worldwide. Although it exhibits multiple symptoms, facial paralysis has not been previously documented as a noticeable presentation.Case Presentation In this case, we report a 40-year-old male who presented with facial numbness and pain for one month, weakness of his facial muscles for 15 days, and recurrent right epistaxis for 1 year. He had a history of nasal inflammatory polyps with chronic sinusitis. Computed tomography and magnetic resonance imaging showed space-occupying lesions in the right nasal cavity and maxillary sinus, with bone destruction occurring in the sinus wall and turbinate. This patient then underwent endoscopic surgery. According to the histopathological and immunohistochemical Results , he was eventually diagnosed with paranasal sinus angiosarcoma in April 2021. To date, this patient has not initiated any radiotherapy or chemotherapy and has survived with lymphatic metastasis for at least 3 years.Conclusions This manuscript suggests that paranasal sinus angiosarcoma can present with facial paralysis. Moreover, pathological and immunohistochemical tests are still vital for diagnosing paranasal sinus angiosarcoma and differential diagnosis. Additionally, regular follow-up is crucial for patients with paranasal sinus angiosarcoma, enabling monitoring of recurrence, metastasis, and recovery while contributing valuable clinical data to understanding this rare disease and associated research endeavours. | Keywords: | Paranasal sinus angiosarcoma Facial paralysis Pathology Immunohistochemistry Case report |
Publisher: | BioMed Central Ltd. | Journal: | BMC Neurology | EISSN: | 1471-2377 | DOI: | 10.1186/s12883-023-03482-2 | Rights: | Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data. The following publication Chai, C., Feng, X., Li, K. et al. Paranasal sinus angiosarcoma with facial paralysis as a novel manifestation: a case report and literature review. BMC Neurol 23, 428 (2023) is available at https://dx.doi.org/10.1186/s12883-023-03482-2. |
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