Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/105817
DC Field | Value | Language |
---|---|---|
dc.contributor | Mainland Development Office | - |
dc.creator | Yuan, R | - |
dc.creator | Qiao, X | - |
dc.creator | Tang, C | - |
dc.creator | Zhou, T | - |
dc.creator | Chen, W | - |
dc.creator | Song, R | - |
dc.creator | Jiang, Y | - |
dc.creator | Reinhardt, JD | - |
dc.creator | Wang, H | - |
dc.date.accessioned | 2024-04-23T04:31:32Z | - |
dc.date.available | 2024-04-23T04:31:32Z | - |
dc.identifier.uri | http://hdl.handle.net/10397/105817 | - |
dc.language.iso | en | en_US |
dc.publisher | MDPI AG | en_US |
dc.rights | Copyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). | en_US |
dc.rights | The following publication Yuan R, Qiao X, Tang C, Zhou T, Chen W, Song R, Jiang Y, Reinhardt JD, Wang H. Effects of Uni- vs. Bilateral Upper Limb Robot-Assisted Rehabilitation on Motor Function, Activities of Daily Living, and Electromyography in Hemiplegic Stroke: A Single-Blinded Three-Arm Randomized Controlled Trial. Journal of Clinical Medicine. 2023; 12(8):2950 is available at https://doi.org/10.3390/jcm12082950. | en_US |
dc.subject | Motor evoked potential | en_US |
dc.subject | Motor function | en_US |
dc.subject | Stroke | en_US |
dc.subject | Surface electromyography | en_US |
dc.subject | Upper limb robot-assisted rehabilitation | en_US |
dc.title | Effects of uni- vs. bilateral upper limb robot-assisted rehabilitation on motor function, activities of daily living, and electromyography in hemiplegic stroke : a single-blinded three-arm randomized controlled trial | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.volume | 12 | - |
dc.identifier.issue | 8 | - |
dc.identifier.doi | 10.3390/jcm12082950 | - |
dcterms.abstract | Objective: To evaluate if bilateral or unilateral upper limb robot-assisted rehabilitation training using a new three-dimensional end-effector robot that targets shoulder and elbow flexion and abduction is superior to conventional therapy with regard to upper extremity motor function recovery and neuromuscular improvement in stroke patients. Design: Randomized, controlled, parallel, assessor-blinded, three-arm clinical trial. Setting: Southeast University Zhongda Hospital Nanjing, Jiangsu, China. Methods: Seventy patients with hemiplegic stroke were randomly assigned to conventional training (Control, n = 23) or unilateral (URT, n = 23), or bilateral robotic training (BRT, n = 24). The conventional group received routine rehabilitation, 60 min/day, 6 days/week, for 3 weeks. For URT and BRT upper limb robot-assisted rehabilitation training was added. This was 60 min/day, 6 days/week, for 3 weeks. The primary outcome was upper limb motor function assessed with Fugl-Meyer–Upper Extremity Scale (FMA–UE). Secondary outcomes were activities of daily living (ADL) assessed with the Modified Barthel Index (MBI), Motor Evoked Potential (MEP) to assess corticospinal tract connectivity, Root Mean Square (RMS) value, and integrate Electromyography (iEMG) value recorded by surface electromyography to evaluate muscle contraction function. Results: The primary outcome indicator FMA–UE (least square mean (LSMEAN): 31.40, 95% confidence interval (95% CI): 27.74–35.07) and the secondary outcome indicator MBI (LSMEAN: 69.95, 95% CI: 66.69–73.21) were significantly improved in BRT as opposed to control (FMA–UE, LSMEAN: 24.79, 95% CI: 22.23–27.35; MBI, LSMEAN: 62.75, 95% CI: 59.42–66.09); and unilateral (FMA–UE, LSMEAN: 25.97, 95% CI: 23.57–28.36; MBI, LSMEAN: 64.34, 95% CI: 61.01–67.68). BRT also showed greater improvement in the anterior deltoid bundle with regard to muscle contraction function indicated by RMS (LSMEAN: 257.79, 95% CI: 211.45–304.12) and iEMG (LSMEAN: 202.01, 95% CI: 167.09–236.94), as compared to the controls (RMS, LSMEAN: 170.77, 95% CI: 148.97–192.58; iEMG, LSMEAN: 132.09, 95% CI: 114.51–149.68), and URT (RMS, LSMEAN: 179.05, 95% CI: 156.03–202.07; iEMG, LSMEAN: 130.38, 95% CI: 107.50–153.26). There was no statistically significant difference between URT and conventional training for any outcome. There was no significant difference in MEP extraction rate after treatment between groups (p = 0.54 for URT, p = 0.08 for BRT). Conclusions: A 60 min daily training for upper extremities using a three-dimensional end-effector targeting elbow and shoulder adding conventional rehabilitation appears to promote upper limb function and ADL in stroke patients only if delivered bilaterally. URT does not seem to result in better outcomes than conventional rehabilitation. Electrophysiological results suggest that training using a bilateral upper limb robot increases the recruitment of motor neurons rather than improving the conduction function of the corticospinal tract. | - |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Journal of clinical medicine, Apr. 2023, v. 12, no. 8, 2950 | - |
dcterms.isPartOf | Journal of clinical medicine | - |
dcterms.issued | 2023-04 | - |
dc.identifier.scopus | 2-s2.0-85154555791 | - |
dc.identifier.eissn | 2077-0383 | - |
dc.identifier.artn | 2950 | - |
dc.description.validate | 202404 bcch | - |
dc.description.oa | Version of Record | en_US |
dc.identifier.FolderNumber | OA_Scopus/WOS | en_US |
dc.description.fundingSource | Others | en_US |
dc.description.fundingText | National Key Research and Development Program of China; Jiangsu Key Research and Development Program; Horizontal Project of Nanjing Estun Co., LTD fund | en_US |
dc.description.pubStatus | Published | en_US |
dc.description.oaCategory | CC | en_US |
Appears in Collections: | Journal/Magazine Article |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
jcm-12-02950.pdf | 1.11 MB | Adobe PDF | View/Open |
Page views
13
Citations as of Jun 30, 2024
Downloads
2
Citations as of Jun 30, 2024
SCOPUSTM
Citations
3
Citations as of Jul 4, 2024
WEB OF SCIENCETM
Citations
4
Citations as of Jul 4, 2024
![](/image/google_scholar.jpg)
Google ScholarTM
Check
Altmetric
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.