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http://hdl.handle.net/10397/105793
Title: | A review on the sources, structures, and pharmacological activities of lucidenic acids | Authors: | Zheng, C Rangsinth, P Shiu, PHT Wang, W Li, R Li, J Kwan, YW |
Issue Date: | Feb-2023 | Source: | Molecules, Feb. 2023, v.28, no. 4, 1756 | Abstract: | Ganoderma lucidum has long been used as a multi-purpose plant and functional food. The pharmacological properties of G. lucidum are primarily attributed to its polysaccharides and triterpenoids. Ganoderic and lucidenic acids are the two major triterpenoids groups in G. lucidum. Despite the discovery of 22 types of lucidenic acids, research on lucidenic acids is significantly less extensive compared to that on ganoderic acid. To the best of our knowledge, for the first time, in this review, we aimed to summarize the sources, contents, chemical structures, and pharmacological effects, including anti-cancer, anti-inflammatory, antioxidant, anti-viral, neuroprotective, anti-hyperlipidemic, anti-hypercholesterolemic, and anti-diabetic properties, of lucidenic acids. Studies on lucidenic acids are still preliminary and have several limitations. Therefore, more in-depth studies with optimal designs are essential for the development of lucidenic acids as medicines, functional foods, and nutraceuticals. | Keywords: | Ganoderma lucidum Lucidenic acids Pharmacological effects |
Publisher: | MDPI AG | Journal: | Molecules | EISSN: | 1420-3049 | DOI: | 10.3390/molecules28041756 | Rights: | Copyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). The following publication Zheng C, Rangsinth P, Shiu PHT, Wang W, Li R, Li J, Kwan Y-W, Leung GPH. A Review on the Sources, Structures, and Pharmacological Activities of Lucidenic Acids. Molecules. 2023; 28(4):1756 is available at https://doi.org/10.3390/molecules28041756. |
Appears in Collections: | Journal/Magazine Article |
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