Maximal incremental exercise improves macular photostress recovery time and lowers intraocular pressure in healthy athletes

Abstract

Objectives: Better visual performance in athletes compared to non-athletes could suggest improved macular function through physical exertion. The study aimed to investigate the effect of maximal incremental treadmill (MIT) exercise on macular function. Design: An interventional study comparing the effect of maximal incremental treadmill (MIT) exercise until volitional exhaustion between athletes (n = 26) and non-athletes (n = 26). Methods: Participants underwent an ophthalmological assessment involving repeated measurements of the photostress recovery time (PSRT) at baseline and post-exercise. PSRT was recorded after a 10-second exposure of the macular to an intense light source from an ophthalmoscope positioned 2 cm in front of the eye. Secondary outcome measures also recorded included the best-corrected visual acuity (BCVA) and the intraocular pressure (IOP). Results: Compared to the baseline, MIT exercise markedly improved the PSRT of athletes from 42.7 ± 1.6 s to 39.6 ± 1.4 s (P < 0.001), while having no significant changes in the PSRT of non-athletes. After adjusting for exercise duration, the exercise intervention showed significant effects on the PSRT improvement in the athletes compared to non-athletes after exercise [F(1,49) = 16.941, P < 0.001], with estimated marginal means of 3.00 s and 0.47 s, respectively. Also, the exercise intervention resulted in significant improvements in IOP (P < 0.001) and BCVA (P < 0.01) of both groups. Conclusions: MIT exercise improves macular function, BCVA, and reduced IOP in healthy athletes. Maximal incremental exercise may be recommended for competitive sports athletes seeking optimal visual performance, as long as it does not adversely impact other relevant non-visual factors.