Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/101586
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dc.contributorDepartment of Applied Biology and Chemical Technology-
dc.creatorTsoi, THen_US
dc.creatorGu, YJen_US
dc.creatorLo, WSen_US
dc.creatorWong, WTen_US
dc.creatorWong, WTen_US
dc.creatorNg, CFen_US
dc.creatorLee, CSen_US
dc.creatorWong, KLen_US
dc.date.accessioned2023-09-18T07:31:19Z-
dc.date.available2023-09-18T07:31:19Z-
dc.identifier.urihttp://hdl.handle.net/10397/101586-
dc.language.isoenen_US
dc.publisherJohn Wiley & Sonsen_US
dc.rights© 2017 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheimen_US
dc.rightsThis is the peer reviewed version of the following article: T.-H. Tsoi, Y.-J. Gu, W.-S. Lo, W.-T. Wong, W.-T. Wong, C.-F. Ng, C.-S. Lee, K.-L. Wong, Study of the Aggregation of DNA-Capped Gold Nanoparticles: A Smart and Flexible Aptasensor for Spermine Sensing. ChemPlusChem 2017, 82, 802-809, which has been published in final form at https://doi.org/10.1002/cplu.201700155. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited.en_US
dc.subjectDNAen_US
dc.subjectGolden_US
dc.subjectNanoparticlesen_US
dc.subjectSpermineen_US
dc.subjectUrineen_US
dc.titleStudy of the aggregation of DNA-capped gold nanoparticles : a smart and flexible aptasensor for spermine sensingen_US
dc.typeJournal/Magazine Articleen_US
dc.identifier.spage802en_US
dc.identifier.epage809en_US
dc.identifier.volume82en_US
dc.identifier.issue5en_US
dc.identifier.doi10.1002/cplu.201700155en_US
dcterms.abstractA smart gold nanoparticle based aptasensor is developed for the sensing of this biomarker in a convenient and fast manner. A comprehensive study was performed to elucidate the driving force of DNA adsorption, different factors’ effects, such as gold nanoparticle size, DNA length, concentration, and working pH towards spermine sensing by using UV/Vis absorption spectroscopy and isothermal titration calorimetry. It was found that the developed aptasensor could detect spermine by two different sensing mechanisms simply by adjusting the DNA concentration without complicated procedures. Good performance in complicated matrices was proven by the satisfactory results obtained in the spike analysis of both artificial urine and clinical urine samples. Such a flexible and smart approach described here would provide a useful tool for the fast sensing of spermine and prostate cancer screening.-
dcterms.accessRightsopen accessen_US
dcterms.bibliographicCitationChemPlusChem, May 2017, v. 82, no. 5, p. 802-809en_US
dcterms.isPartOfChemPlusChemen_US
dcterms.issued2017-05-
dc.identifier.scopus2-s2.0-85019981471-
dc.identifier.pmid31961525-
dc.identifier.eissn2192-6506en_US
dc.description.validate202308 bckw-
dc.description.oaAccepted Manuscripten_US
dc.identifier.FolderNumberABCT-0652-
dc.description.fundingSourceOthersen_US
dc.description.fundingTextThe University Research Facility for Chemical and Environmental Analysis (UCEA); Area of Excellent Grants of The Hong Kong Polytechnic University; Matching Proof-of-Concept Fund of Hong Kong Baptist University; Shenzhen Science and Technology Innovation Committeeen_US
dc.description.pubStatusPublisheden_US
dc.identifier.OPUS6749802-
dc.description.oaCategoryGreen (AAM)en_US
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