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Title: Parity-time symmetry based on resonant optical tunneling effect for biosensing
Authors: Jian, A
Liu, F
Bai, G
Zhang, B
Zhang, Y
Zhang, Q
Xue, X
Sang, S
Zhang, X 
Issue Date: 15-Nov-2020
Source: Optics communications, 15 Nov. 2020, v. 475, 125815
Abstract: This paper proposes and analyzes a parity-time (PT) symmetry structure based on resonant optical tunneling effect (ROTE) by using two directly coupled ROTE resonators to achieve a balanced gain-loss distribution. The unbroken/broken states of the PT symmetric system are theoretically verified by coupled-mode theory (CMT), transmission matrix method (TMM) and finite-difference time-domain (FDTD). To demonstrate the application potential, we further propose a label-free biosensing scheme that takes advantages of the square-root dependence in frequency splitting near exceptional point (EP). The theoretical results show that the sensor has a maximum sensitivity of 1 × 105 nm/IP unit (imaginary part unit of refractive index) and a theoretical detection limit of 5 × 10−10 IP unit (corresponds to 0.4 ng carcinoembryonic antigen (CEA)). Compared with the PT systems based on coupled waveguides or resonators, our design has some distinctive features. It is a multi-layer structure and does not need complicated nanoscale fabrication; the liquid samples “flow-through” the sensing region in the mid of PT structure and would greatly enhance the analyte binding efficiency as compared with the common “flow-over” manner. This simple yet highly sensitive platform would find applications in biomedical sensors, drinking water safety, and drug screening.
Keywords: Parity-time (PT) symmetry
Resonant optical tunneling effect (ROTE)
Exceptional point (EP)
Biosensing
Carcinoembryonic antigen (CEA)
Publisher: Elsevier
Journal: Optics communications 
ISSN: 0030-4018
EISSN: 1873-0310
DOI: 10.1016/j.optcom.2020.125815
Rights: © 2020 Elsevier B.V. All rights reserved.
© 2020. This manuscript version is made available under the CC-BY-NC-ND 4.0 license https://creativecommons.org/licenses/by-nc-nd/4.0/
The following publication Jian, A., Liu, F., Bai, G., Zhang, B., Zhang, Y., Zhang, Q., ... & Zhang, X. (2020). Parity-time symmetry based on resonant optical tunneling effect for biosensing. Optics Communications, 475, 125815 is available at https://doi.org/10.1016/j.optcom.2020.125815.
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