Application of CM-Phos ligand in palladium-catalyzed cross-coupling reactions

Abstract

Palladium-catalyzed cross-coupling is one of the most effective and widely utilized tools for connecting electrophilic and nucleophilic coupling partners for carbon-carbon or carbon-heteroatom bonds forming reactions. 2-[2-(dicyclohexylphosphino)phenyl]-N-methylindole(CM-Phos) ligand derivatives have proven to be successful catalysts in this context. This review summarizes the recent developments, and applications of different coupling partners in these reactions by using CM-Phos ligand derivatives. 本文综合评述了近年来2-[2-(二环己膦基)苯基]-1-甲基-1H-吲哚(CM-Phos)膦配体及其衍生物在钯催化的交叉偶联反应中的应用，主要根据不同种类的交叉偶联反应进行系统性分述，并对该领域的发展前景进行了展望。