Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/91679
PIRA download icon_1.1View/Download Full Text
Title: A fluorescent probe for the discrimination of oxidation states of palladium
Authors: Jiang, LJ 
Mak, HN 
Walter, ERH
Wong, WT 
Wong, KL
Long, NJ
Issue Date: 2021
Source: Chemical science, 2021, https://doi.org/10.1039/d1sc01616d
Abstract: Palladium-based catalysts are widely used in pharmaceutical industries, which can sometimes cause palladium contamination in pharmaceutical drug manufacture. It is important to separately quantify the different oxidation states of palladium (Pd-0 and Pd2+) in pharmaceuticals as they react with scavengers differently. Although palladium sensors have been under intense investigation, oxidation state differentiators are very rare. Here, we report a simple porphyrin-coumarin conjugate, PPIX-L2, that can selectively discriminate between the oxidation states of palladium. The reaction of PPIX-L2 with Pd-0 showed a 24-fold fluorescence increase of the coumarin emission, meanwhile, the presence of Pd2+ led to a 98% quenching of the porphyrin emission. Fluorescent responses of PPIX-L2 towards Pd-0 and Pd2+ are specific, and its sensitivity towards both palladium species is significantly increased with a detection limit of 75 nM and 382 nM for Pd-0 and Pd2+ respectively.
Publisher: Royal Society of Chemistry
Journal: Chemical science 
ISSN: 2041-6520
EISSN: 2041-6539
DOI: 10.1039/d1sc01616d
Rights: © 2021 The Author(s). Published by the Royal Society of Chemistry
This article is licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported Licence. (https://creativecommons.org/licenses/by-nc/3.0/)
The following publication Jiang, L., Mak, H. N., Walter, E. R., Wong, W. T., Wong, K. L., & Long, N. J. (2021). A fluorescent probe for the discrimination of oxidation states of palladium. Chemical Science, 12(29), 9977-9982 is available at http://dx.doi.org/10.1039/D1SC01616D
Appears in Collections:Journal/Magazine Article

Files in This Item:
File Description SizeFormat 
Jiang_fluorescent_probe_discrimination.pdf1.01 MBAdobe PDFView/Open
Open Access Information
Status open access
File Version Version of Record
Access
View full-text via PolyU eLinks SFX Query
Show full item record

Page views

36
Citations as of May 22, 2022

Downloads

9
Citations as of May 22, 2022

SCOPUSTM   
Citations

3
Citations as of May 27, 2022

WEB OF SCIENCETM
Citations

1
Citations as of May 26, 2022

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.