Please use this identifier to cite or link to this item: http://hdl.handle.net/10397/81358
PIRA download icon_1.1View/Download Full Text
Title: Substrate-related factors affecting cellulosome-induced hydrolysis for lignocellulose valorization
Authors: Wang, Y 
Leng, L
Islam, MK 
Liu, FH
Lin, CSK
Leu, SY 
Issue Date: 2019
Source: International journal of molecular sciences, 1 July 2019, v. 20, no. 13, 3354, p. 1-17
Abstract: Cellulosomes are an extracellular supramolecular multienzyme complex that can efficiently degrade cellulose and hemicelluloses in plant cell walls. The structural and unique subunit arrangement of cellulosomes can promote its adhesion to the insoluble substrates, thus providing individual microbial cells with a direct competence in the utilization of cellulosic biomass. Significant progress has been achieved in revealing the structures and functions of cellulosomes, but a knowledge gap still exists in understanding the interaction between cellulosome and lignocellulosic substrate for those derived from biorefinery pretreatment of agricultural crops. The cellulosomic saccharification of lignocellulose is affected by various substrate-related physical and chemical factors, including native (untreated) wood lignin content, the extent of lignin and xylan removal by pretreatment, lignin structure, substrate size, and of course substrate pore surface area or substrate accessibility to cellulose. Herein, we summarize the cellulosome structure, substrate-related factors, and regulatory mechanisms in the host cells. We discuss the latest advances in specific strategies of cellulosome-induced hydrolysis, which can function in the reaction kinetics and the overall progress of biorefineries based on lignocellulosic feedstocks.
Keywords: Cellulosome
Lignocellulose
Substrate-related factors
Enzymatic hydrolysis
Bioproducts
Reaction kinetics
Publisher: Molecular Diversity Preservation International (MDPI)
Journal: International journal of molecular sciences 
ISSN: 1661-6596
EISSN: 1422-0067
DOI: 10.3390/ijms20133354
Rights: © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
The following publication Wang, Y.; Leng, L.; Islam, M.K.; Liu, F.; Lin, C.S.K.; Leu, S.-Y. Substrate-Related Factors Affecting Cellulosome-Induced Hydrolysis for Lignocellulose Valorization. Int. J. Mol. Sci. 2019, 20, 3354, 1-17 is available at https://dx.doi.org/10.3390/ijms20133354
Appears in Collections:Journal/Magazine Article

Files in This Item:
File Description SizeFormat 
Wang_Substrate-Related_Cellulosome-Induced_Hydrolysis.pdf1.84 MBAdobe PDFView/Open
Open Access Information
Status open access
File Version Version of Record
Access
View full-text via PolyU eLinks SFX Query
Show full item record

Page views

105
Citations as of May 22, 2022

Downloads

67
Citations as of May 22, 2022

SCOPUSTM   
Citations

16
Citations as of May 26, 2022

WEB OF SCIENCETM
Citations

13
Citations as of May 26, 2022

Google ScholarTM

Check

Altmetric


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.