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Title: Anxiety and depressive symptoms in college students during the late stage of the COVID-19 outbreak : a network approach
Authors: Bai, W
Cai, H
Liu, S
Chen, X
Sha, S
Cheung, T 
Lin, JJ 
Cui, X
Ng, CH
Xiang, YT
Issue Date: 17-Dec-2021
Source: Translational Psychiatry, 17 Dec. 2021, v. 11, no. 1, 638
Abstract: Mental health problems are common in college students even in the late stage of the coronavirus disease 2019 (COVID-19) outbreak. Network analysis is a novel approach to explore interactions of mental disorders at the symptom level. The aim of this study was to elucidate characteristics of depressive and anxiety symptoms network in college students in the late stage of the COVID-19 outbreak. A total of 3062 college students were included. The seven-item Generalized Anxiety Disorder Scale (GAD-7) and nine-item Patient Health Questionnaire (PHQ-9) were used to measure anxiety and depressive symptoms, respectively. Central symptoms and bridge symptoms were identified based on centrality and bridge centrality indices, respectively. Network stability was examined using the case-dropping procedure. The strongest direct relation was between anxiety symptoms “Nervousness” and “Uncontrollable worry”. “Fatigue” has the highest node strength in the anxiety and depression network, followed by “Excessive worry”, “Trouble relaxing”, and “Uncontrollable worry”. “Motor” showed the highest bridge strength, followed by “Feeling afraid” and “Restlessness”. The whole network was robust in both stability and accuracy tests. Central symptoms “Fatigue”, “Excessive worry”, “Trouble relaxing” and “Uncontrollable worry”, and critical bridge symptoms “Motor”, “Feeling afraid” and “Restlessness” were highlighted in this study. Targeting interventions to these symptoms may be important to effectively alleviate the overall level of anxiety and depressive symptoms in college students.
Publisher: Nature Publishing Group
Journal: Translational psychiatry 
EISSN: 2158-3188
DOI: 10.1038/s41398-021-01738-4
Rights: © The Author(s) 2021
Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons. org/licenses/by/4.0/.
The following publication Bai, W., Cai, H., Liu, S. et al. Anxiety and depressive symptoms in college students during the late stage of the COVID-19 outbreak: a network approach. Transl Psychiatry 11, 638 (2021) is available at https://doi.org/10.1038/s41398-021-01738-4.
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