Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/96574
DC Field | Value | Language |
---|---|---|
dc.contributor | Department of Health Technology and Informatics | - |
dc.creator | Cheung, AHY | en_US |
dc.creator | Wu, VWC | en_US |
dc.creator | Cheung, ALY | en_US |
dc.creator | Cai, J | en_US |
dc.date.accessioned | 2022-12-07T02:55:29Z | - |
dc.date.available | 2022-12-07T02:55:29Z | - |
dc.identifier.uri | http://hdl.handle.net/10397/96574 | - |
dc.language.iso | en | en_US |
dc.publisher | Frontiers Research Foundation | en_US |
dc.rights | © 2022 Cheung, Wu, Cheung and Cai. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. | en_US |
dc.rights | The following publication Cheung, A. H. Y., Wu, V. W. C., Cheung, A. L. Y., & Cai, J. (2022). Respiratory 4D-gating F-18 FDG PET/CT scan for liver malignancies: Feasibility in liver cancer patient and tumor quantitative analysis. Frontiers in oncology, 12, 789506 is available at https://doi.org/10.3389/fonc.2022.789506. | en_US |
dc.subject | 4D PET/CT | en_US |
dc.subject | Clinical protocol | en_US |
dc.subject | Liver | en_US |
dc.subject | Respiratory gated PET/CT | en_US |
dc.subject | SUV | en_US |
dc.title | Respiratory 4D-gating F-18 FDG PET/CT scan for liver malignancies : feasibility in liver cancer patient and tumor quantitative analysis | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.volume | 12 | en_US |
dc.identifier.doi | 10.3389/fonc.2022.789506 | en_US |
dcterms.abstract | Purpose: To evaluate the potential clinical role and effectiveness of respiratory 4D-gating F-18 FDG PET/CT scan for liver malignancies, relative to routine (3D) F-18 FDG PET/CT scan. | - |
dcterms.abstract | Materials and Methods: This study presented a prospective clinical study of 16 patients who received F-18 FDG PET/CT scan for known or suspected malignant liver lesions. Ethics approvals were obtained from the ethics committees of the Hong Kong Baptist Hospital and The Hong Kong Polytechnic University. Liver lesions were compared between the gated and ungated image sets, in terms of 1) volume measurement of PET image, 2) accuracy of maximum standardized uptake value (SUVmax), mean standardized uptake value (SUVmean), and 3) accuracy of total lesion glycoses (TLG). Statistical analysis was performed by using a two-tailed paired Student t-test and Pearson correlation test. | - |
dcterms.abstract | Results: The study population consisted of 16 patients (9 males and 7 females; mean age of 65) with a total number of 89 lesions. The SUVmax and SUVmean measurement of the gated PET images was more accurate than that of the ungated PET images, compared to the static reference images. An average of 21.48% (p < 0.001) reduction of the tumor volume was also observed. The SUVmax and SUVmean of the gated PET images were improved by 19.81% (p < 0.001) and 25.53% (p < 0.001), compared to the ungated PET images. | - |
dcterms.abstract | Conclusions: We have demonstrated the feasibility of implementing 4D PET/CT scan for liver malignancies in a prospective clinical study. The 4D PET/CT scan for liver malignancies could improve the quality of PET image by improving the SUV accuracy of the lesions and reducing image blurring. The improved accuracy in the classification and identification of liver tumors with 4D PET image would potentially lead to its increased utilization in target delineation of GTV, ITV, and PTV for liver radiotherapy treatment planning in the future. | - |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Frontiers in oncology, Feb. 2022, v. 12, 789506 | en_US |
dcterms.isPartOf | Frontiers in oncology | en_US |
dcterms.issued | 2022-02 | - |
dc.identifier.scopus | 2-s2.0-85125299117 | - |
dc.identifier.eissn | 2234-943X | en_US |
dc.identifier.artn | 789506 | en_US |
dc.description.validate | 202212 bckw | - |
dc.description.oa | Version of Record | en_US |
dc.identifier.FolderNumber | OA_Scopus/WOS | - |
dc.description.pubStatus | Published | en_US |
Appears in Collections: | Journal/Magazine Article |
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File | Description | Size | Format | |
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fonc-12-789506.pdf | 2.54 MB | Adobe PDF | View/Open |
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