Please use this identifier to cite or link to this item:
http://hdl.handle.net/10397/94986
DC Field | Value | Language |
---|---|---|
dc.contributor | School of Optometry | en_US |
dc.contributor | School of Optometry | en_US |
dc.contributor | Research Centre for SHARP Vision | en_US |
dc.creator | Choi, KY | en_US |
dc.creator | Chan, HHL | en_US |
dc.date.accessioned | 2022-09-08T02:58:05Z | - |
dc.date.available | 2022-09-08T02:58:05Z | - |
dc.identifier.issn | 0146-0404 | en_US |
dc.identifier.uri | http://hdl.handle.net/10397/94986 | - |
dc.language.iso | en | en_US |
dc.publisher | Association for Research in Vision and Ophthalmology | en_US |
dc.rights | Copyright 2021 The Authors | en_US |
dc.rights | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/). | en_US |
dc.rights | The following publication Choi KY, Chan HHL. Extrinsic and intrinsic factors regulating juvenile refractive development and eye growth. Invest Ophthalmol Vis Sci. 2021;62(14):21 is available at https://doi.org/10.1167/iovs.62.14.21. | en_US |
dc.subject | Myopia | en_US |
dc.subject | Environment | en_US |
dc.subject | Nearwork | en_US |
dc.subject | Accommodation | en_US |
dc.subject | Peripheral refraction | en_US |
dc.title | Extrinsic and intrinsic factors regulating juvenile refractive development and eye growth | en_US |
dc.type | Journal/Magazine Article | en_US |
dc.identifier.volume | 62 | en_US |
dc.identifier.issue | 14 | en_US |
dc.identifier.doi | 10.1167/iovs.62.14.21 | en_US |
dcterms.abstract | Purpose: Peripheral refraction and accommodation are intrinsic factors that were once hypothesized to trigger myopia but are now controversial. Previously, home nearwork environment (i.e., extrinsic factor) was reported to be associated with myopia progression. In this study, we aimed to evaluate the potential interaction between extrinsic and intrinsic factors with juvenile refractive development. | en_US |
dcterms.abstract | Methods: Nearwork environmental parameters were measured for 50 children (aged 9.3 ± 1.2 years), including net amount and dispersion of defocus. Refraction was measured at near distances and in central field (±30° horizontal) at 3m. The relative peripheral refraction (RPRE) was obtained and presented in a vectoral approach. The linear regression coefficient was extracted (mAcc) from the accommodative stimulus–response curve. RPRE was quadratically regressed against field eccentricity, and the first coefficients (aM, aJ0, aP90, and aP180) were extracted. Relationships between RPRE, baseline accommodation, and 1-year myopia progression (∆M), controlled for the nearwork environment, were evaluated. | en_US |
dcterms.abstract | Results: Coefficients of RPRE were independent of ∆M. However, additional nearwork environmental parameters significantly improved the variance in ∆M explained by aM and aP180 (P < 0.03). The relationship between intrinsic factor and ∆M was stronger when the extrinsic risk was low (P ≤ 0.01), whereas the relationship was abolished when extrinsic risk was high. For mAcc, it also significantly improved the variance in ∆M explained by nearwork environmental parameters. | en_US |
dcterms.abstract | Conclusions: The interaction between extrinsic (environment) and intrinsic (RPRE and accommodation) factors is speculated to contribute to juvenile myopia progression. Our findings may also explain the inconsistencies of such intrinsic factors in the literature. | en_US |
dcterms.accessRights | open access | en_US |
dcterms.bibliographicCitation | Investigative ophthalmology and visual science, Nov. 2021, v. 62, no. 14, 21 | en_US |
dcterms.isPartOf | Investigative ophthalmology and visual science | en_US |
dcterms.issued | 2021-11 | - |
dc.identifier.isi | WOS:000726739200003 | - |
dc.identifier.scopus | 2-s2.0-85121032215 | - |
dc.identifier.pmid | 34797905 | - |
dc.identifier.eissn | 1552-5783 | en_US |
dc.identifier.artn | 21 | en_US |
dc.description.validate | 202209 bcwh | en_US |
dc.description.oa | Version of Record | en_US |
dc.identifier.FolderNumber | SO-0103 | - |
dc.description.fundingSource | RGC | en_US |
dc.description.fundingSource | Others | en_US |
dc.description.fundingText | Collaborative Research (Industrial) Fund from SEED Co. Ltd. (ZG7B) | en_US |
dc.description.fundingText | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (https://creativecommons.org/licenses/by-nc-nd/4.0/). | en_US |
dc.description.pubStatus | Published | en_US |
dc.identifier.OPUS | 61118593 | - |
Appears in Collections: | Journal/Magazine Article |
Files in This Item:
File | Description | Size | Format | |
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i1552-5783-62-14-21_1637310645.54907.pdf | 1.1 MB | Adobe PDF | View/Open |
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